Luo CH, Rudy Y. (1991). A model of the ventricular cardiac action potential. Depolarization, repolarization, and their interaction. Circ Res 68 [PubMed]

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References and models cited by this paper

Adam DR, SMITH JM, Akselrod S, Nyberg S, Powell AO, Cohen RJ. (1984). Fluctuations in T-wave morphology and susceptibility to ventricular fibrillation. J Electrocardiol 17 [PubMed]

Beeler GW, Reuter H. (1977). Reconstruction of the action potential of ventricular myocardial fibres. J Physiol 268 [PubMed]

Berman MF, Camardo JS, Robinson RB, Siegelbaum SA. (1989). Single sodium channels from canine ventricular myocytes: voltage dependence and relative rates of activation and inactivation. J Physiol 415 [PubMed]

Bodewei R, Hering S, Lemke B, Rosenshtraukh LV, Undrovinas AI, Wollenberger A. (1982). Characterization of the fast sodium current in isolated rat myocardial cells: simulation of the clamped membrane potential. J Physiol 325 [PubMed]

Brown AM, Lee KS, Powell T. (1981). Sodium current in single rat heart muscle cells. J Physiol 318 [PubMed]

Chialvo DR, Michaels DC, Jalife J. (1990). Supernormal excitability as a mechanism of chaotic dynamics of activation in cardiac Purkinje fibers. Circ Res 66 [PubMed]

Chiu SY. (1977). Inactivation of sodium channels: second order kinetics in myelinated nerve. J Physiol 273 [PubMed]

Cleemann L, Morad M. (1979). Potassium currents in frog ventricular muscle: evidence from voltage clamp currents and extracellular K accumulation. J Physiol 286 [PubMed]

Colatsky TJ. (1980). Voltage clamp measurements of sodium channel properties in rabbit cardiac Purkinje fibres. J Physiol 305 [PubMed]

Coraboeuf E, Deroubaix E, Coulombe A. (1979). Effect of tetrodotoxin on action potentials of the conducting system in the dog heart. Am J Physiol 236 [PubMed]

Delmar M, Glass L, Michaels DC, Jalife J. (1989). Ionic basis and analytical solution of the wenckebach phenomenon in guinea pig ventricular myocytes. Circ Res 65 [PubMed]

Delmar M, Michaels DC, Jalife J. (1989). Slow recovery of excitability and the Wenckebach phenomenon in the single guinea pig ventricular myocyte. Circ Res 65 [PubMed]

Dennis JE, Gay DM, Welsch RE. (1981). An adaptive nonlinear leastsquares algorithm ACM Transactions On Mathematical Software 7

DiFrancesco D, Noble D. (1985). A model of cardiac electrical activity incorporating ionic pumps and concentration changes. Philos Trans R Soc Lond B Biol Sci 307 [PubMed]

Drouhard JP, Roberge FA. (1987). Revised formulation of the Hodgkin-Huxley representation of the sodium current in cardiac cells. Comput Biomed Res 20 [PubMed]

Ebihara L, Johnson EA. (1980). Fast sodium current in cardiac muscle. A quantitative description. Biophys J 32 [PubMed]

Ebihara L, Shigeto N, Lieberman M, Johnson EA. (1980). The initial inward current in spherical clusters of chick embryonic heart cells. J Gen Physiol 75 [PubMed]

Ebihara L, Shigeto N, Lieberman M, Johnson EA. (1983). A note on the reactivation of the fast sodium current in spherical clusters of embryonic chick heart cells. Biophys J 42 [PubMed]

Elharrar V, Surawicz B. (1983). Cycle length effect on restitution ofaction potential duration in dog cardiac fibers Am J Physiol 244

Frame LH, Simson MB. (1988). Oscillations of conduction, action potential duration, and refractoriness. A mechanism for spontaneous termination of reentrant tachycardias. Circulation 78 [PubMed]

French RJ, Horn R. (1983). Sodium channel gating: models, mimics, and modifiers. Annu Rev Biophys Bioeng 12 [PubMed]

Gettes LS, Reuter H. (1974). Slow recovery from inactivation of inward currents in mammalian myocardial fibres. J Physiol 240 [PubMed]

Grant AO, Starmer CF. (1987). Mechanisms of closure of cardiac sodium channels in rabbit ventricular myocytes: single-channel analysis. Circ Res 60 [PubMed]

Guevara MR, Jeandupeux D, Alonso F, Morissette N. (1989). Wenckebach rhythms in isolated ventricular heart cells Singular Behavior and Nonlinear Dynamics 2

Guevara MR, Jeandupeux D, Alonso F, Van_Ginneken ACG. (1989). Alternans in periodically stimulated isolated ventricular myocytes: Experiment and model Cell to Cell Signalling: From Experments to Theoretical Models

Haas HG, Kern R, Einwächter HM, Tarr M. (1971). Kinetics of Na inactivation in frog atria. Pflugers Arch 323 [PubMed]

Hirano Y, Hiraoka M. (1986). Changes in K+ currents induced by Ba2+ in guinea pig ventricular muscles. Am J Physiol 251 [PubMed]

Hodgkin AL, Huxley AF. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol 117 [PubMed]

Hoff HE, Nahum LH. (1938). The supernormal period in the mammalian ventricle Am J Physiol 124

Horn R, Vandenberg CA. (1984). Statistical properties of single sodium channels. J Gen Physiol 84 [PubMed]

Hume JR, Uehara A. (1985). Ionic basis of the different action potential configurations of single guinea-pig atrial and ventricular myocytes. J Physiol 368 [PubMed]

Iijima T, Taira N. (1987). Pinacidil increases the background potassium current in single ventricular cells. Eur J Pharmacol 141 [PubMed]

Isenberg G. (1976). Cardiac Purkinje fibers: cesium as a tool to block inward rectifying potassium currents. Pflugers Arch 365 [PubMed]

Isenberg G, Klöckner U. (1982). Isolated bovine ventricular myocytes. Characterization of the action potential. Pflugers Arch 395 [PubMed]

Jalife J, MOE GK. (1981). Excitation, conduction, and reflection of impulses in isolated bovine and serum cardiac purkinje fibers. Circ Res 49 [PubMed]

Kakei M, Yoshinaga M, Saito K, Tanaka H. (1986). The potassium current activated by 2-nicotinamidoethyl nitrate (nicorandil) in single ventricular cells of guinea pigs. Proc R Soc Lond B Biol Sci 229 [PubMed]

Kamp TJ, Sanguinetti MC, Miller RJ. (1989). Voltage- and use-dependent modulation of cardiac calcium channels by the dihydropyridine (+)-202-791. Circ Res 64 [PubMed]

Kirsch GE, Brown AM. (1989). Kinetic properties of single sodium channels in rat heart and rat brain. J Gen Physiol 93 [PubMed]

Kiyosue T, Arita M. (1989). Late sodium current and its contribution to action potential configuration in guinea pig ventricular myocytes. Circ Res 64 [PubMed]

Klockner U, Isenberg G. (1982). Calcium tolerant ventricular myocytes prepared by preincubation in a "KB medium". Pflugers Arch 395

Kunze DL, Lacerda AE, Wilson DL, Brown AM. (1985). Cardiac Na currents and the inactivating, reopening, and waiting properties of single cardiac Na channels. J Gen Physiol 86 [PubMed]

Kurachi Y. (1985). Voltage-dependent activation of the inward-rectifier potassium channel in the ventricular cell membrane of guinea-pig heart. J Physiol 366 [PubMed]

Leblanc N, Hume JR. (1990). Sodium current-induced release of calcium from cardiac sarcoplasmic reticulum. Science 248 [PubMed]

Lesh MD, Pring M, Spear JF. (1989). Cellular uncoupling can unmask dispersion of action potential duration in ventricular myocardium. A computer modeling study. Circ Res 65 [PubMed]

MOORE JW, Ramon F. (1974). On numerical integration of the Hodgkin and Huxley equations for a membrane action potential. J Theor Biol 45 [PubMed]

Makielski JC, Sheets MF, Hanck DA, January CT, Fozzard HA. (1987). Sodium current in voltage clamped internally perfused canine cardiac Purkinje cells. Biophys J 52 [PubMed]

Matsuura H, Ehara T, Imoto Y. (1987). An analysis of the delayed outward current in single ventricular cells of the guinea-pig. Pflugers Arch 410 [PubMed]

McAllister RE, Noble D, Tsien RW. (1975). Reconstruction of the electrical activity of cardiac Purkinje fibres. J Physiol 251 [PubMed]

Mcdonald TF, TRAUTWEIN W. (1978). The potassium current underlying delayed rectification in cat ventricular muscle. J Physiol 274 [PubMed]

Nilius B. (1988). Calcium block of guinea-pig heart sodium channels with and without modification by the piperazinylindole DPI 201-106. J Physiol 399 [PubMed]

Patlak JB, Ortiz M. (1985). Slow currents through single sodium channels of the adult rat heart. J Gen Physiol 86 [PubMed]

Quan W, Rudy Y. (1990). Unidirectional block and reentry of cardiac excitation: a model study. Circ Res 66 [PubMed]

Robinson RB, Boyden PA, HOFFMAN BF, Hewett KW. (1987). Electrical restitution process in dispersed canine cardiac Purkinje and ventricular cells. Am J Physiol 253 [PubMed]

Rudy Y, Quan W. (1989). The effects of the discrete cellular structureon propagation of excitation in cardiac tissue: A model study Cell Interactions and Gap Junctions

Rudy Y, Quan WL. (1987). A model study of the effects of the discrete cellular structure on electrical propagation in cardiac tissue. Circ Res 61 [PubMed]

Rush S, Larsen H. (1978). A practical algorithm for solving dynamic membrane equations. IEEE Trans Biomed Eng 25 [PubMed]

Sakmann B, Trube G. (1984). Conductance properties of single inwardly rectifying potassium channels in ventricular cells from guinea-pig heart. J Physiol 347 [PubMed]

Sakmann B, Trube G. (1984). Voltage-dependent inactivation of inward-rectifying single-channel currents in the guinea-pig heart cell membrane. J Physiol 347 [PubMed]

Scanley BE, Hanck DA, Chay T, Fozzard HA. (1990). Kinetic analysis of single sodium channels from canine cardiac Purkinje cells. J Gen Physiol 95 [PubMed]

Shah AK, Cohen IS, Datyner NB. (1987). Background K+ current in isolated canine cardiac Purkinje myocytes. Biophys J 52 [PubMed]

Shibasaki T. (1987). Conductance and kinetics of delayed rectifier potassium channels in nodal cells of the rabbit heart. J Physiol 387 [PubMed]

Spear JF, Moore EN. (1974). The effect of changes in rate and rhythm on supernormal excitability in the isolated Purkinje system of the dog. A possible role in re-entrant arrhythmias. Circulation 50 [PubMed]

Tseng GN, Robinson RB, HOFFMAN BF. (1987). Passive properties and membrane currents of canine ventricular myocytes. J Gen Physiol 90 [PubMed]

Victorri B, Vinet A, Roberge FA, Drouhard JP. (1985). Numerical integration in the reconstruction of cardiac action potentials using Hodgkin-Huxley-type models. Comput Biomed Res 18 [PubMed]

WEIDMANN S. (1955). Effects of calcium ions and local anesthetics on electrical properties of Purkinje fibres. J Physiol 129 [PubMed]

WEIDMANN S. (1970). Electrical constants of trabecular muscle from mammalian heart. J Physiol 210 [PubMed]

Wenckebach KF. (1899). Zur Analyse des unregel massingen Pulses: II. Uber den regelmassig intermittirenden Puls Z F Klin Med 37

Yue DT, Lawrence JH, Marban E. (1989). Two molecular transitions influence cardiac sodium channel gating. Science 244 [PubMed]

Yue DT, Marban E. (1988). A novel cardiac potassium channel that is active and conductive at depolarized potentials. Pflugers Arch 413 [PubMed]

Zilberter YI, Timin EN, Bendukidze ZA, Burnashev NA. (1982). Patch-voltage-clamp method for measuring fast inward current in single rat heart muscle cells. Pflugers Arch 394 [PubMed]

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