Altomare C et al. (2001). Integrated allosteric model of voltage gating of HCN channels. The Journal of general physiology. 117 [PubMed]
Altomare C et al. (2003). Heteromeric HCN1-HCN4 channels: a comparison with native pacemaker channels from the rabbit sinoatrial node. The Journal of physiology. 549 [PubMed]
Azene EM, Xue T, Marbán E, Tomaselli GF, Li RA. (2005). Non-equilibrium behavior of HCN channels: insights into the role of HCN channels in native and engineered pacemakers. Cardiovascular research. 67 [PubMed]
Baruscotti M, Bucchi A, Difrancesco D. (2005). Physiology and pharmacology of the cardiac pacemaker ("funny") current. Pharmacology & therapeutics. 107 [PubMed]
Chen J, Mitcheson JS, Lin M, Sanguinetti MC. (2000). Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel. The Journal of biological chemistry. 275 [PubMed]
Chen S, Wang J, Siegelbaum SA. (2001). Properties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotide. The Journal of general physiology. 117 [PubMed]
DiFrancesco D. (1993). Pacemaker mechanisms in cardiac tissue. Annual review of physiology. 55 [PubMed]
HODGKIN AL, HUXLEY AF. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. The Journal of physiology. 117 [PubMed]
Hahin R. (1988). Removal of inactivation causes time-invariant sodium current decays. The Journal of general physiology. 92 [PubMed]
Halliwell JV, Adams PR. (1982). Voltage-clamp analysis of muscarinic excitation in hippocampal neurons. Brain research. 250 [PubMed]
Larsson HP, Elinder F. (2000). A conserved glutamate is important for slow inactivation in K+ channels. Neuron. 27 [PubMed]
Ludwig A et al. (2003). Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2. The EMBO journal. 22 [PubMed]
Ludwig A, Zong X, Hofmann F, Biel M. (1999). Structure and function of cardiac pacemaker channels. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 9 [PubMed]
Ludwig A, Zong X, Jeglitsch M, Hofmann F, Biel M. (1998). A family of hyperpolarization-activated mammalian cation channels. Nature. 393 [PubMed]
López-Barneo J, Hoshi T, Heinemann SH, Aldrich RW. (1993). Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels. Receptors & channels. 1 [PubMed]
Magee JC. (1998). Dendritic hyperpolarization-activated currents modify the integrative properties of hippocampal CA1 pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18 [PubMed]
Moroni A et al. (2001). Hyperpolarization-activated cyclic nucleotide-gated channel 1 is a molecular determinant of the cardiac pacemaker current I(f). The Journal of biological chemistry. 276 [PubMed]
Männikkö R, Elinder F, Larsson HP. (2002). Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages. Nature. 419 [PubMed]
Männikkö R, Pandey S, Larsson HP, Elinder F. (2005). Hysteresis in the voltage dependence of HCN channels: conversion between two modes affects pacemaker properties. The Journal of general physiology. 125 [PubMed]
Nolan MF et al. (2003). The hyperpolarization-activated HCN1 channel is important for motor learning and neuronal integration by cerebellar Purkinje cells. Cell. 115 [PubMed]
Olcese R, Latorre R, Toro L, Bezanilla F, Stefani E. (1997). Correlation between charge movement and ionic current during slow inactivation in Shaker K+ channels. The Journal of general physiology. 110 [PubMed]
Pape HC. (1996). Queer current and pacemaker: the hyperpolarization-activated cation current in neurons. Annual review of physiology. 58 [PubMed]
Robinson RB, Siegelbaum SA. (2003). Hyperpolarization-activated cation currents: from molecules to physiological function. Annual review of physiology. 65 [PubMed]
Santoro B et al. (1998). Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain. Cell. 93 [PubMed]
Santoro B, Tibbs GR. (1999). The HCN gene family: molecular basis of the hyperpolarization-activated pacemaker channels. Annals of the New York Academy of Sciences. 868 [PubMed]
Schulze-Bahr E et al. (2003). Pacemaker channel dysfunction in a patient with sinus node disease. The Journal of clinical investigation. 111 [PubMed]
Shi W et al. (1999). Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues. Circulation research. 85 [PubMed]
Shin KS, Maertens C, Proenza C, Rothberg BS, Yellen G. (2004). Inactivation in HCN channels results from reclosure of the activation gate: desensitization to voltage. Neuron. 41 [PubMed]
Tokimasa T, Akasu T. (1990). Cyclic AMP regulates an inward rectifying sodium-potassium current in dissociated bull-frog sympathetic neurones. The Journal of physiology. 420 [PubMed]
Ueda K et al. (2004). Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia. The Journal of biological chemistry. 279 [PubMed]
Ulens C, Tytgat J. (2001). Functional heteromerization of HCN1 and HCN2 pacemaker channels. The Journal of biological chemistry. 276 [PubMed]
Wang J, Chen S, Nolan MF, Siegelbaum SA. (2002). Activity-dependent regulation of HCN pacemaker channels by cyclic AMP: signaling through dynamic allosteric coupling. Neuron. 36 [PubMed]
Zagotta WN, Hoshi T, Dittman J, Aldrich RW. (1994). Shaker potassium channel gating. II: Transitions in the activation pathway. The Journal of general physiology. 103 [PubMed]
Zhang H et al. (2000). Mathematical models of action potentials in the periphery and center of the rabbit sinoatrial node. American journal of physiology. Heart and circulatory physiology. 279 [PubMed]