The Hodgkin-Huxley equations (HH) are parameterized by a number of parameters and shows a variety of qualitatively different behaviors depending on the parameter values. Under stimulation of an external periodic voltage, the ISIs (interspike intervals) of a HH model are investigated in this work, while the frequency of the voltage is taken as the controlling parameter. As well-known, the science of acupuncture and moxibustion is an important component of Traditional Chinese Medicine with a long history. Although there are a number of different acupuncture manipulations, the method for distinguishing them is rarely investigated. With the idea of ISI, we study the electrical signal time series at the spinal dorsal horn produced by three different acupuncture manipulations in Zusanli point and present an effective way to distinguish them.
Model Type: Axon
Cell Type(s): Squid axon
Currents: I Sodium; I Potassium
Model Concept(s): Bursting; Oscillations; Simplified Models; Axonal Action Potentials; Action Potentials; Complementary and alternative medicine
Simulation Environment: XPPAUT
Implementer(s): Wu, Sheng-Nan [snwu at mail.ncku.edu.tw]; Wu, Yung-Hun
References:
Wang J, Si W, Che Y, Fei x. (2008). Spike trains in Hodgkin–Huxley model and of acupuncture manipulations Chaos, Solitons and Fractals. 36