Interacting synaptic conductances during, distorting, voltage clamp (Poleg-Polsky and Diamond 2011)

This simulation examines the accuracy of the voltage clamp technique in detecting the excitatory and the inhibitory components of the synaptic drive.

Model Type: Neuron or other electrically excitable cell

Currents: I N; I K

Receptors: GabaA; AMPA; NMDA

Transmitters: Gaba; Glutamate

Model Concept(s): Influence of Dendritic Geometry; Detailed Neuronal Models; Synaptic Integration

Simulation Environment: NEURON

Implementer(s): Polsky, Alon [alonpol at tx.technion.ac.il]

References:

Diamond JS, Polsky A. (2011). Imperfect Space Clamp Permits Electrotonic Interactions between Inhibitory and Excitatory Synaptic Conductances, Distorting Voltage Clamp Recordings. PLoS ONE. 6(4)