Using a previous model of respiratory rhythm generation, we modified the network architecture such that cells can be segregated into two clusters. Cells within a given cluster burst with smaller phase differences than do cells from different clusters. This may explain the large phase differences seen experimentally, as reported in the paper.
Model Type: Realistic Network
Model Concept(s): Activity Patterns; Bursting; Respiratory control
Simulation Environment: NEURON
Implementer(s): Fietkiewicz, Chris
References:
Fietkiewicz C, Loparo KA, Wilson CG. (2011). Drive latencies in hypoglossal motoneurons indicate developmental change in the brainstem respiratory network. Journal of neural engineering. 8 [PubMed]