Active dendritic action potential propagation (Casale & McCormick 2011)

This model explores the dendritic sodium and potassium conductances needed to recapitulate voltage-sensitive dye optical recordings of thalamic interneuron dendrites in the dorsal lateral geniculate nucleus. Model ion channels were selected based on pharmacological data.

Model Type: Neuron or other electrically excitable cell

Region(s) or Organism(s): Thalamus

Cell Type(s): Thalamus lateral geniculate nucleus interneuron

Currents: I Na,t; I_KHT

Model Concept(s): Dendritic Action Potentials; Conductance distributions

Simulation Environment: NEURON

Implementer(s): Casale, Amanda [Amanda.Casale at yale.edu]

References:

Casale AE, McCormick DA. (2011). Active action potential propagation but not initiation in thalamic interneuron dendrites. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31 [PubMed]