NMDA subunit effects on Calcium and STDP (Evans et al. 2012)

Effect of NMDA subunit on spike timing dependent plasticity.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Neostriatum medium spiny direct pathway GABA cell

Currents: I Na,t; I L high threshold; I T low threshold; I A; I h; I K,Ca; I Calcium; I A, slow

Receptors: GabaA; Glutamate

Model Concept(s): STDP; Calcium dynamics

Simulation Environment: GENESIS

Implementer(s): Blackwell, Avrama [avrama at gmu.edu]; Evans, Rebekah [Rebekah.Evans at nih.gov]

References:

Evans RC et al. (2012). The effects of NMDA subunit composition on calcium influx and spike timing-dependent plasticity in striatal medium spiny neurons. PLoS computational biology. 8 [PubMed]