Human sleep/wake cycle (Rempe et al. 2010)


This model simulates sleep in the human brain and is consistent with both the flip/flop concept and the two-process model of sleep regulation. The model also gives a possible mechanism for the changes in sleep timing seen in narcolepsy.

Model Type: Realistic Network

Transmitters: Gaba

Model Concept(s): Sleep

Simulation Environment: XPPAUT

Implementer(s): Rempe, Michael [mrempe at whitworth.edu]

References:

Rempe MJ, Best J, Terman D. (2010). A mathematical model of the sleep/wake cycle. Journal of mathematical biology. 60 [PubMed]

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