A 1000 cell network model for Lateral Amygdala (Kim et al. 2013)


1000 Cell Lateral Amygdala model for investigation of plasticity and memory storage during Pavlovian Conditioning.

Model Type: Realistic Network; Neuron or other electrically excitable cell; Synapse; Dendrite

Region(s) or Organism(s): Amygdala

Cell Type(s): Hippocampus CA1 pyramidal GLU cell; Hippocampus CA3 pyramidal GLU cell; Hodgkin-Huxley neuron

Currents: I Na,t; I L high threshold; I A; I M; I Sodium; I Calcium; I Potassium; I_AHP; Ca pump

Receptors: AMPA; NMDA; Gaba; Dopaminergic Receptor

Transmitters: Dopamine; Norephinephrine

Model Concept(s): Synaptic Plasticity; Short-term Synaptic Plasticity; Long-term Synaptic Plasticity; Learning; Neuromodulation

Simulation Environment: NEURON

Implementer(s): Kim, Dongbeom [dk258 at mail.missouri.edu]

References:

Kim D, Paré D, Nair SS. (2013). Mechanisms contributing to the induction and storage of Pavlovian fear memories in the lateral amygdala. Learn Mem 20 [PubMed]