1000 Cell Lateral Amygdala model for investigation of plasticity and memory storage during Pavlovian Conditioning.
Model Type: Realistic Network; Neuron or other electrically excitable cell; Synapse; Dendrite
Region(s) or Organism(s): Amygdala
Cell Type(s): Hippocampus CA1 pyramidal GLU cell; Hippocampus CA3 pyramidal GLU cell; Hodgkin-Huxley neuron
Currents: I Na,t; I L high threshold; I A; I M; I Sodium; I Calcium; I Potassium; I_AHP; Ca pump
Receptors: AMPA; NMDA; Gaba; Dopaminergic Receptor
Transmitters: Dopamine; Norephinephrine
Model Concept(s): Synaptic Plasticity; Short-term Synaptic Plasticity; Long-term Synaptic Plasticity; Learning; Neuromodulation
Simulation Environment: NEURON
Implementer(s): Kim, Dongbeom [dk258 at mail.missouri.edu]
References:
Kim D, Paré D, Nair SS. (2013). Mechanisms contributing to the induction and storage of Pavlovian fear memories in the lateral amygdala. Learning & memory (Cold Spring Harbor, N.Y.). 20 [PubMed]