Understanding odor information segregation in the olfactory bulb by MC/TCs (Polese et al. 2014)


Odor identification is one of the main tasks of the olfactory system. It is performed almost independently from the concentration of the odor providing a robust recognition. This capacity to ignore concentration information does not preclude the olfactory system from estimating concentration itself. Significant experimental evidence has indicated that the olfactory system is able to infer simultaneously odor identity and intensity. However, it is still unclear at what level or levels of the olfactory pathway this segregation of information occurs. In this work, we study whether this odor information segregation is performed at the input stage of the olfactory bulb: the glomerular layer.

Model Type: Realistic Network

Cell Type(s): Olfactory bulb main mitral GLU cell; Olfactory bulb main interneuron periglomerular GABA cell; Olfactory bulb main tufted middle GLU cell; Olfactory bulb short axon cell

Model Concept(s): Action Potentials; Olfaction

Simulation Environment: MATLAB

References:

Polese D, Martinelli E, Marco S, Di Natale C, Gutierrez-Galvez A. (2014). Understanding odor information segregation in the olfactory bulb by means of mitral and tufted cells. PloS one. 9 [PubMed]


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