Axon-somatic back-propagation in a detailed model of cat spinal motoneuron (Balbi et al, 2015)


Morphologically detailed conductance-based models of cat spinal alpha motoneurons have been developed, with the aim to reproduce and clarify some aspects of the electrophysiological behavior of the antidromic axon-somatic spike propagation. Fourteen 3D morphologically detailed somata and dendrites of cat spinal alpha motoneurons have been imported from an open-access web-based database of neuronal morphologies, NeuroMorpho.org, and instantiated in neurocomputational models.

Model Type: Neuron or other electrically excitable cell

Region(s) or Organism(s): Spinal motoneuron

Cell Type(s): Spinal cord lumbar motor neuron alpha ACh cell

Currents: I Na,p; I Na,t; I K; I h; I K,Ca; I Calcium

Simulation Environment: NEURON

Implementer(s): Balbi, Pietro [piero.balbi at fsm.it]

References:

Balbi P, Martinoia S, Massobrio P. (2015). Axon-somatic back-propagation in detailed models of spinal alpha motoneurons. Front Comput Neurosci 9 [PubMed]