NETMORPH: creates NNs with realistic neuron morphologies (Koene et al. 2009, van Ooyen et al. 2014)


NETMORPH is a simulation tool for building synaptically connected networks with realistic neuron morphologies. Axonal and dendritic morphologies are created by using stochastic rules for the behavior of individual growth cones, the structures at the tip of outgrowing axons and dendrites that mediate elongation and branching. Axons and dendrites are not guided by any extracellular cues. Synapses are formed when crossing axonal and dendritic segments come sufficiently close to each other. See the README in the archive for more information.

Model Type: Realistic Network; Neuron or other electrically excitable cell

Model Concept(s): Methods

Simulation Environment: C or C++ program

References:

Koene RA et al. (2009). NETMORPH: a framework for the stochastic generation of large scale neuronal networks with realistic neuron morphologies. Neuroinformatics. 7 [PubMed]

van Ooyen A et al. (2014). Independently outgrowing neurons and geometry-based synapse formation produce networks with realistic synaptic connectivity. PloS one. 9 [PubMed]


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