Synaptic integration in a model of granule cells (Gabbiani et al 1994)


We have developed a compartmental model of a turtle cerebellar granule cell consisting of 13 compartments that represent the soma and 4 dendrites. We used this model to investigate the synaptic integration of mossy fiber inputs in granule cells. See reference or abstract at PubMed link below for more information.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Cerebellum interneuron granule GLU cell

Currents: I Na,t; I L high threshold; I K; I h; I K,Ca

Receptors: GabaA; AMPA; NMDA

Model Concept(s): Action Potential Initiation; Coincidence Detection; Detailed Neuronal Models; Action Potentials; Calcium dynamics

Simulation Environment: NEURON

Implementer(s): Gabbiani, F

References:

Gabbiani F, Midtgaard J, Knöpfel T. (1994). Synaptic integration in a model of cerebellar granule cells. J Neurophysiol 72 [PubMed]