"... Using a multi-subunit nonlinear model, we demonstrate that stimulus selectivity can arise from the spatial distribution of synapses. We propose this as a general mechanism for information processing by neurons possessing dendritic trees. Moreover, we show that this implementation of stimulus selectivity increases the neuron's robustness to synaptic and dendritic failure. ..."
Model Type: Neuron or other electrically excitable cell
Receptors: NMDA
Model Concept(s): Stimulus selectivity
Simulation Environment: NEURON (web link to model); Python (web link to model)
References:
Cazé RD, Jarvis S, Foust AJ, Schultz SR. (2017). Dendrites Enable a Robust Mechanism for Neuronal Stimulus Selectivity. Neural computation. 29 [PubMed]