"The fly visual system offers a unique opportunity to explore computations performed by single neurons. Two previous studies characterized, in vivo, the receptive field (RF) of the vertical system (VS) cells of the blowfly (calliphora vicina), both intracellularly in the axon, and, independently using Ca2+ imaging, in hundreds of distal dendritic branchlets. We integrated this information into detailed passive cable and compartmental models of 3D reconstructed VS cells. Within a given VS cell type, the transfer resistance (TR) from different branchlets to the axon differs substantially, suggesting that they contribute unequally to the shaping of the axonal RF. ..."
Model Type: Axon
Cell Type(s): Fly lobular plate vertical system cell
Model Concept(s): Detailed Neuronal Models
Simulation Environment: NEURON
Implementer(s): Dan, Ohad [Ohad.Dan at gmail.com]
References:
Dan O, Hopp E, Borst A, Segev I. (2018). Non-uniform weighting of local motion inputs underlies dendritic computation in the fly visual system. Scientific reports. 8 [PubMed]