GC model (Beining et al 2017)


A companion modeldb entry (NEURON only) to modeldb accession number 231862.

Model Type: Neuron or other electrically excitable cell

Region(s) or Organism(s): Dentate gyrus

Cell Type(s): Dentate gyrus granule GLU cell

Currents: I A; I Calcium; I h; I K; I K,Ca; I K,leak; I Na,t; I M; Kir2 leak

Genes: Cav1.2 CACNA1C; Cav1.3 CACNA1D; Cav2.2 CACNA1B; Cav3.2 CACNA1H; HCN1; Nav1.2 SCN2A; Nav1.6 SCN8A; Kir2.1 KCNJ2; Kv1.1 KCNA1; Kv1.4 KCNA4; Kv2.1 KCNB1; Kv3.3 KCNC3; Kv3.4 KCNC4; Kv4.2 KCND2; KCa1.1 KCNMA1; KCa2.2 KCNN2

Model Concept(s): Methods; Neurogenesis; Conductance distributions

Simulation Environment: NEURON

Implementer(s): Beining, Marcel [beining at fias.uni-frankfurt.de]

References:

Schwarzacher SW, Cuntz H, Jedlicka P, Beining M, Mongiat LA. (2017). T2N as a new tool for robust electrophysiological modeling demonstrated for mature and adult-born dentate granule cells eLife