Extracellular stimulation of myelinated axon (Reilly 2016)


This is an implementation of an established "electrostimulation model" subjected to a set of stimulation protocols. Such models and protocols are used to predict the response of neural tissue to stimulation by electromagnetic fields or direct application of extracellular current in order to "evaluate the efficacy and safety of medical devices, or to develop guidelines or standards on acceptible incidental exposure that may not be related to patient exposure for medical purposes."

Model Type: Axon

Region(s) or Organism(s): Xenopus

Cell Type(s): Myelinated neuron

Currents: I Sodium; I K

Model Concept(s): Extracellular Fields

Simulation Environment: NEURON

Implementer(s): Carnevale, Ted [Ted.Carnevale at Yale.edu]

References:

Reilly JP. (2016). Survey of numerical electrostimulation models. Phys Med Biol 61 [PubMed]