Biophysical model of CA1 hippocampal region. The model simulates place cells/fields and explores the place cell dynamics as function of VIP+ interneurons.
Model Type: Realistic Network
Region(s) or Organism(s): Hippocampus; Mouse
Cell Type(s): Hippocampus CA1 pyramidal GLU cell; Hippocampus CA1 basket cell; Hippocampus CA1 basket cell - CCK/VIP; Hippocampus CA1 bistratified cell; Hippocampus CA1 axo-axonic cell; Hippocampus CA1 stratum oriens lacunosum-moleculare interneuron ; Hippocampal CA1 CR/VIP cell
Currents: I A; I h; I K,Ca; I Calcium; I Na, leak; I K,leak; I M
Receptors: GabaA; GabaB; NMDA; AMPA
Model Concept(s): Place cell/field
Simulation Environment: NEURON; Brian
Implementer(s): Chavlis, Spyridon [schavlis at imbb.forth.gr]; Pandi, Ioanna
References:
Turi GF et al. (2019). Vasoactive Intestinal Polypeptide-Expressing Interneurons in the Hippocampus Support Goal-Oriented Spatial Learning Neuron.