"... we investigated the channel mechanism regulating the motoneuron recruitment. Three types of motoneuron pools including slow (S), fatigue-resistant (FR) and fast-fatigable (FF) motoneurons were constructed based on the membrane proprieties of cat lumbar motoneurons. The transient sodium (NaT), persistent sodium (NaP), delayed-rectifier potassium [K(DR)], Ca2+-dependent K+ [K(AHP)] and L-type calcium (CaL) channels were included in the models..."
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Spinal cord motor neuron fast fatiguing; Spinal cord motor neuron fatigue resistant; Spinal cord motor neuron slow twitch
Currents: I Na,t; I Na,p; I K; I_AHP; I L high threshold
Simulation Environment: NEURON
Implementer(s): Zhang, Qiang
References:
Zhang Q, Dai Y. (2020). A modeling study of spinal motoneuron recruitment regulated by ionic channels during fictive locomotion Journal of computational neuroscience. 48 [PubMed]