Leech Mechanosensory Neurons: Synaptic Facilitation by Reflected APs (Baccus 1998)


This model by Stephen Baccus explores the phenomena of action potential (AP) propagation at branch boints in axons. APs are sometimes transmitted down the efferent processes and sometimes are reflected back to the axon of AP origin or neither. See the paper for details. The model zip file contains a readme.txt which list introductory steps to follow to run the simulation. Stephen Baccus's email address: baccus@fas.harvard.edu

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Leech pressure (P) mechanosensory neuron

Currents: I K; I K,Ca; I Sodium; I Calcium; I Potassium

Model Concept(s): Action Potential Initiation; Pattern Recognition; Activity Patterns; Spatio-temporal Activity Patterns; Influence of Dendritic Geometry; Detailed Neuronal Models; Synaptic Plasticity; Short-term Synaptic Plasticity; Axonal Action Potentials; Action Potentials; Facilitation; Invertebrate

Simulation Environment: NEURON

Implementer(s): Baccus, Stephen [Baccus at fas.Harvard.edu]

References:

Baccus SA. (1998). Synaptic facilitation by reflected action potentials: enhancement of transmission when nerve impulses reverse direction at axon branch points. Proc Natl Acad Sci U S A 95 [PubMed]