We have developed a model for the rat phrenic motor neuron (PMN) that robustly replicates many experimentally observed behaviors of PMNs in response to pharmacological, ionic, and electrical perturbations using a single set of parameters.
Model Type: Neuron or other electrically excitable cell
Currents: I Na,p; I Na,t; I L high threshold; I N; I T low threshold; I K,Ca
Model Concept(s): Ion Channel Kinetics; Action Potentials; Spike Frequency Adaptation
Simulation Environment: C or C++ program (web link to model)
References:
Amini B, Bidani A, Zwischenberger JB, Clark JW. (2004). A model of the rat phrenic motor neuron. IEEE transactions on bio-medical engineering. 51 [PubMed]