Spike Initiation in Neocortical Pyramidal Neurons (Mainen et al 1995)

This model reproduces figure 3A from the paper Mainen ZF, Joerges J, Huguenard JR, Sejnowski TJ (1995). Please see the paper for detail whose full text is available at http://www.cnl.salk.edu/~zach/methods.html Email Zach Mainen for questions: mainen@cshl.org

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Myelinated neuron

Currents: I Na,p; I K

Model Concept(s): Action Potential Initiation; Dendritic Action Potentials; Active Dendrites; Influence of Dendritic Geometry; Detailed Neuronal Models; Axonal Action Potentials

Simulation Environment: NEURON

Implementer(s): Mainen, Zach [Mainen at cshl.edu]

References:

Mainen ZF, Joerges J, Huguenard JR, Sejnowski TJ. (1995). A model of spike initiation in neocortical pyramidal neurons. Neuron. 15 [PubMed]