Temperature-Sensitive conduction at axon branch points (Westerfield et al 1978)


Propagation of impulses through branching regions of squid axons was examined experimentally and with computer simulations. The ratio of postbranch/prebranch diameters at which propagation failed was very sensitive to temperature.

Model Type: Axon

Currents: I Na,t; I K

Model Concept(s): Axonal Action Potentials; Conduction failure

Simulation Environment: NEURON

Implementer(s): Hines, Michael [Michael.Hines at Yale.edu]

References:

Westerfield M, Joyner RW, MOORE JW. (1978). Temperature-sensitive conduction failure at axon branch points. J Neurophysiol 41 [PubMed]