Beeler GW, Reuter H. (1977). Reconstruction of the action potential of ventricular myocardial fibres. The Journal of physiology. 268 [PubMed]
Bers DM. (2001). Excitation-Contraction Coupling and Cardiac Contractile Force (2nd edn).
Bers DM, Yuan W, Pogwizd SM, Puglisi JL. (2000). Increased Na-Ca exchange and reduced IK1 facilitate triggered action potentials in a rabbit model of heart failure Biophys J. 78
Brown PB, Malhotra L. (1978). A 60-Hz harmonic eliminator. IEEE transactions on bio-medical engineering. 25 [PubMed]
Callewaert G, Sipido KR, Carmeliet E. (1993). [Ca2+]i transients and [Ca2+]i-dependent chloride current in single Purkinje cells from rabbit heart. J Physiol. 468
Carmeliet E. (1999). Cardiac ionic currents and acute ischemia: from channels to arrhythmias. Physiological reviews. 79 [PubMed]
DiFrancesco D, Noble D. (1985). A model of cardiac electrical activity incorporating ionic pumps and concentration changes. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 307 [PubMed]
HODGKIN AL, HUXLEY AF. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. The Journal of physiology. 117 [PubMed]
Hilgemann DW, Noble D. (1987). Excitation-contraction coupling and extracellular calcium transients in rabbit atrium: reconstruction of basic cellular mechanisms. Proceedings of the Royal Society of London. Series B, Biological sciences. 230 [PubMed]
Hiraoka M, Kawano S. (1989). Calcium-sensitive and insensitive transient outward current in rabbit ventricular myocytes. The Journal of physiology. 410 [PubMed]
Hiraoka M, Kawano S, Hirayama Y. (1995). Activation mechanism of Ca(2+)-sensitive transient outward current in rabbit ventricular myocytes. J Physiol. 486 ( Pt 3)
Jafri MS, Rice JJ, Winslow RL. (1998). Cardiac Ca2+ dynamics: the roles of ryanodine receptor adaptation and sarcoplasmic reticulum load. Biophysical journal. 74 [PubMed]
Kawano S, Hiraoka M. (1991). Transient outward currents and action potential alterations in rabbit ventricular myocytes. Journal of molecular and cellular cardiology. 23 [PubMed]
Lindblad DS et al. (2004). Mathematical model of an adult human atrial cell: the role of K+ currents in repolarization. Circ Res. 82
Lindblad DS, Murphey CR, Clark JW, Giles WR. (1996). A model of the action potential and underlying membrane currents in a rabbit atrial cell. The American journal of physiology. 271 [PubMed]
Luo CH, Rudy Y. (1991). A model of the ventricular cardiac action potential. Depolarization, repolarization, and their interaction. Circulation research. 68 [PubMed]
Luo CH, Rudy Y. (1994). A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes. Circulation research. 74 [PubMed]
McAllister RE, Noble D, Tsien RW. (1975). Reconstruction of the electrical activity of cardiac Purkinje fibres. The Journal of physiology. 251 [PubMed]
NOBLE D. (1962). A modification of the Hodgkin--Huxley equations applicable to Purkinje fibre action and pace-maker potentials. The Journal of physiology. 160 [PubMed]
Nerbonne JM. (2000). Molecular basis of functional voltage-gated K+ channel diversity in the mammalian myocardium. The Journal of physiology. 525 Pt 2 [PubMed]
Noble D, Tsien RW. (1968). The kinetics and rectifier properties of the slow potassium current in cardiac Purkinje fibres. The Journal of physiology. 195 [PubMed]
Nordin C. (1993). Computer model of membrane current and intracellular Ca2+ flux in the isolated guinea pig ventricular myocyte. The American journal of physiology. 265 [PubMed]
Pogwizd SM, Chung MK, Cain ME. (1997). Termination of ventricular tachycardia in the human heart. Insights from three-dimensional mapping of nonsustained and sustained ventricular tachycardias. Circulation. 95 [PubMed]
Pogwizd SM, Qi M, Yuan W, Samarel AM, Bers DM. (1999). Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure. Circulation research. 85 [PubMed]
Pogwizd SM, Schlotthauer K, Li L, Yuan W, Bers DM. (2001). Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. Circulation research. 88 [PubMed]
Priebe L, Beuckelmann DJ. (1998). Simulation study of cellular electric properties in heart failure. Circulation research. 82 [PubMed]
Puglisi JL, Yuan W, Bassani JW, Bers DM. (1999). Ca(2+) influx through Ca(2+) channels in rabbit ventricular myocytes during action potential clamp: influence of temperature. Circulation research. 85 [PubMed]
Shannon TR, Bers DM. (2001). A mathematical model describes the SR load-dependence of Ca dynamics in cardiac myocytes Biophys J. 80
Shannon TR, Ginsburg KS, Bers DM. (2000). Reverse mode of the sarcoplasmic reticulum calcium pump and load-dependent cytosolic calcium decline in voltage-clamped cardiac ventricular myocytes. Biophysical journal. 78 [PubMed]
Shannon TR, Ginsburg KS, Bers DM. (2000). Potentiation of fractional sarcoplasmic reticulum calcium release by total and free intra-sarcoplasmic reticulum calcium concentration. Biophysical journal. 78 [PubMed]
Trafford AW, Díaz ME, Eisner DA. (1999). A novel, rapid and reversible method to measure Ca buffering and time-course of total sarcoplasmic reticulum Ca content in cardiac ventricular myocytes. Pflugers Archiv : European journal of physiology. 437 [PubMed]
Trafford AW, O'Neill SC, Eisner DA, Diaz ME. (1995). Comparison of subsarcolemmal and bulk calcium concentration during spontaneous calcium release in rat ventricular myocytes. J Physiol. 488 ( Pt 3)
Weber CR, Ginsburg KS, Philipson KD, Shannon TR, Bers DM. (2001). Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes. The Journal of general physiology. 117 [PubMed]
Winslow RL, Rice J, Jafri S, Marbán E, O'Rourke B. (1999). Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, II: model studies. Circulation research. 84 [PubMed]
Zeng J, Laurita KR, Rosenbaum DS, Rudy Y. (1995). Two components of the delayed rectifier K+ current in ventricular myocytes of the guinea pig type. Theoretical formulation and their role in repolarization. Circulation research. 77 [PubMed]
Zygmunt AC, Gibbons WR. (1991). Calcium-activated chloride current in rabbit ventricular myocytes. Circulation research. 68 [PubMed]
Zygmunt AC, Gibbons WR. (1992). Properties of the calcium-activated chloride current in heart. The Journal of general physiology. 99 [PubMed]
Busjahn A et al. (2004). Association of the serum and glucocorticoid regulated kinase (sgk1) gene with QT interval. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 14 [PubMed]
Mahajan A et al. (2008). A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates. Biophysical journal. 94 [PubMed]
Patel SP, Campbell DL. (2005). Transient outward potassium current, 'Ito', phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms. The Journal of physiology. 569 [PubMed]
Winslow RL, Cortassa S, Greenstein JL. (2005). Using models of the myocyte for functional interpretation of cardiac proteomic data. The Journal of physiology. 563 [PubMed]
Winslow RL, Greenstein JL. (2004). The ongoing journey to understand heart function through integrative modeling. Circulation research. 95 [PubMed]
Alvarez de la Rosa D, Zhang P, Náray-Fejes-Tóth A, Fejes-Tóth G, Canessa CM. (1999). The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes. The Journal of biological chemistry. 274 [PubMed]
Baillard C et al. (2000). Converting enzyme inhibition normalizes QT interval in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). 36 [PubMed]
Bazett HC. (1920). An Analysis Of The Time Relations of Electrocardiograms. 7
Berger S et al. (1998). Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism. Proceedings of the National Academy of Sciences of the United States of America. 95 [PubMed]
Bhargava A et al. (2001). The serum- and glucocorticoid-induced kinase is a physiological mediator of aldosterone action. Endocrinology. 142 [PubMed]
Biondi RM, Kieloch A, Currie RA, Deak M, Alessi DR. (2001). The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB. The EMBO journal. 20 [PubMed]
Blazer-Yost BL, Liu X, Helman SI. (1998). Hormonal regulation of ENaCs: insulin and aldosterone. The American journal of physiology. 274 [PubMed]
Blazer-Yost BL, Păunescu TG, Helman SI, Lee KD, Vlahos CJ. (1999). Phosphoinositide 3-kinase is required for aldosterone-regulated sodium reabsorption. The American journal of physiology. 277 [PubMed]
Boehmer C et al. (2003). Serum and glucocorticoid inducible kinases in the regulation of the cardiac sodium channel SCN5A. Cardiovascular research. 57 [PubMed]
Boulkroun S et al. (2002). Characterization of rat NDRG2 (N-Myc downstream regulated gene 2), a novel early mineralocorticoid-specific induced gene. The Journal of biological chemistry. 277 [PubMed]
Brennan FE, Fuller PJ. (2000). Rapid upregulation of serum and glucocorticoid-regulated kinase (sgk) gene expression by corticosteroids in vivo. Molecular and cellular endocrinology. 166 [PubMed]
Busjahn A et al. (2002). Serum- and glucocorticoid-regulated kinase (SGK1) gene and blood pressure. Hypertension (Dallas, Tex. : 1979). 40 [PubMed]
Busjahn A et al. (1999). QT interval is linked to 2 long-QT syndrome loci in normal subjects. Circulation. 99 [PubMed]
Busjahn A, Luft FC. (2003). Twin studies in the analysis of minor physiological differences between individuals. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 13 [PubMed]
Böhmer C et al. (2000). The shrinkage-activated Na(+) conductance of rat hepatocytes and its possible correlation to rENaC. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 10 [PubMed]
Chen SY et al. (1999). Epithelial sodium channel regulated by aldosterone-induced protein sgk. Proceedings of the National Academy of Sciences of the United States of America. 96 [PubMed]
Cohen P, Lang F. (2001). Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms. Sci STKE. 2001
Cooper MS et al. (2001). Modulation of 11beta-hydroxysteroid dehydrogenase isozymes by proinflammatory cytokines in osteoblasts: an autocrine switch from glucocorticoid inactivation to activation. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 16 [PubMed]
Cowling RT, Birnboim HC. (2000). Expression of serum- and glucocorticoid-regulated kinase (sgk) mRNA is up-regulated by GM-CSF and other proinflammatory mediators in human granulocytes. Journal of leukocyte biology. 67 [PubMed]
Debonneville C et al. (2001). Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression. The EMBO journal. 20 [PubMed]
Embark HM, Böhmer C, Vallon V, Luft F, Lang F. (2003). Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms. Pflugers Archiv : European journal of physiology. 445 [PubMed]
Fillon S et al. (2002). Expression of the serine/threonine kinase hSGK1 in chronic viral hepatitis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 12 [PubMed]
Firestone GL, Giampaolo JR, O'Keeffe BA. (2003). Stimulus-dependent regulation of serum and glucocorticoid inducible protein kinase (SGK) transcription, subcellular localization and enzymatic activity. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 13 [PubMed]
Friedrich B et al. (2003). The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaC. Pflugers Archiv : European journal of physiology. 445 [PubMed]
Hansson JH et al. (1995). Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndrome. Nature genetics. 11 [PubMed]
Hayashi M et al. (2001). BMK1 mediates growth factor-induced cell proliferation through direct cellular activation of serum and glucocorticoid-inducible kinase. The Journal of biological chemistry. 276 [PubMed]
Henke G, Setiawan I, Böhmer C, Lang F. (2002). Activation of Na+/K+-ATPase by the serum and glucocorticoid-dependent kinase isoforms. Kidney & blood pressure research. 25 [PubMed]
Hummler E et al. (1996). Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice. Nature genetics. 12 [PubMed]
Klingel K et al. (2000). Expression of cell volume-regulated kinase h-sgk in pancreatic tissue. American journal of physiology. Gastrointestinal and liver physiology. 279 [PubMed]
Kobayashi T, Cohen P. (1999). Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2. Biochem J. 339 ( Pt 2)
Kumari S, Liu X, Nguyen T, Zhang X, D'Mello SR. (2001). Distinct phosphorylation patterns underlie Akt activation by different survival factors in neurons. Brain research. Molecular brain research. 96 [PubMed]
Lang F et al. (2003). Regulation of channels by the serum and glucocorticoid-inducible kinase - implications for transport, excitability and cell proliferation. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 13 [PubMed]
Lang F et al. (2000). Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy. Proceedings of the National Academy of Sciences of the United States of America. 97 [PubMed]
Lifton RP. (1996). Molecular genetics of human blood pressure variation. Science (New York, N.Y.). 272 [PubMed]
Loffing J et al. (2001). Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK. American journal of physiology. Renal physiology. 280 [PubMed]
Mikosz CA, Brickley DR, Sharkey MS, Moran TW, Conzen SD. (2001). Glucocorticoid receptor-mediated protection from apoptosis is associated with induction of the serine/threonine survival kinase gene, sgk-1. The Journal of biological chemistry. 276 [PubMed]
Nagy Z et al. (1999). Quantitative trait loci for blood pressure exist near the IGF-1, the Liddle syndrome, the angiotensin II-receptor gene and the renin loci in man. Journal of the American Society of Nephrology : JASN. 10 [PubMed]
Náray-Fejes-Tóth A, Canessa C, Cleaveland ES, Aldrich G, Fejes-Tóth G. (1999). sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial na+ channels. The Journal of biological chemistry. 274 [PubMed]
Náray-Fejes-Tóth A, Fejes-Tóth G, Volk KA, Stokes JB. (2000). SGK is a primary glucocorticoid-induced gene in the human. The Journal of steroid biochemistry and molecular biology. 75 [PubMed]
Park J et al. (1999). Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway. The EMBO journal. 18 [PubMed]
Park J et al. (2000). Hyperosmotic stress stimulates promoter activity and regulates cellular utilization of the serum- and glucocorticoid-inducible protein kinase (Sgk) by a p38 MAPK-dependent pathway. J Biol Chem. 275
Perrotti N, He RA, Phillips SA, Haft CR, Taylor SI. (2001). Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin. The Journal of biological chemistry. 276 [PubMed]
Piccirillo G et al. (2002). QT-interval variability and autonomic control in hypertensive subjects with left ventricular hypertrophy. Clinical science (London, England : 1979). 102 [PubMed]
Prasad N, Topping RS, Zhou D, Decker SJ. (2000). Oxidative stress and vanadate induce tyrosine phosphorylation of phosphoinositide-dependent kinase 1 (PDK1). Biochemistry. 39 [PubMed]
Puglisi JL, Bers DM. (2001). LabHEART: an interactive computer model of rabbit ventricular myocyte ion channels and Ca transport. American journal of physiology. Cell physiology. 281 [PubMed]
Schild L et al. (1996). Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome. The EMBO journal. 15 [PubMed]
Seebohm G, Scherer CR, Busch AE, Lerche C. (2001). Identification of specific pore residues mediating KCNQ1 inactivation. A novel mechanism for long QT syndrome. The Journal of biological chemistry. 276 [PubMed]
Setiawan I et al. (2002). Stimulation of Xenopus oocyte Na(+),K(+)ATPase by the serum and glucocorticoid-dependent kinase sgk1. Pflugers Archiv : European journal of physiology. 444 [PubMed]
Shigaev A, Asher C, Latter H, Garty H, Reuveny E. (2000). Regulation of sgk by aldosterone and its effects on the epithelial Na(+) channel. American journal of physiology. Renal physiology. 278 [PubMed]
Shimkets RA et al. (1994). Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel. Cell. 79 [PubMed]
Snyder PM, Olson DR, Thomas BC. (2002). Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel. The Journal of biological chemistry. 277 [PubMed]
Snyder PM et al. (1995). Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel. Cell. 83 [PubMed]
Staub O et al. (1997). Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination. The EMBO journal. 16 [PubMed]
Vereninov AA et al. (2001). Differential transcription of ion transporters, NHE1, ATP1B1, NKCC1 in human peripheral blood lymphocytes activated to proliferation. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 11 [PubMed]
Vincent GM. (1998). The molecular genetics of the long QT syndrome: genes causing fainting and sudden death. Annual review of medicine. 49 [PubMed]
Waerntges S et al. (2002). Excessive transcription of the human serum and glucocorticoid dependent kinase hSGK1 in lung fibrosis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 12 [PubMed]
Wagner CA et al. (2001). Effects of the serine/threonine kinase SGK1 on the epithelial Na(+) channel (ENaC) and CFTR: implications for cystic fibrosis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 11 [PubMed]
Waldegger S, Barth P, Raber G, Lang F. (1997). Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume. Proceedings of the National Academy of Sciences of the United States of America. 94 [PubMed]
Waldegger S, Gabrysch S, Barth P, Fillon S, Lang F. (2000). h-sgk serine-threonine protein kinase as transcriptional target of p38/MAP kinase pathway in HepG2 human hepatoma cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 10 [PubMed]
Waldegger S et al. (1999). h-sgk serine-threonine protein kinase gene as transcriptional target of transforming growth factor beta in human intestine. Gastroenterology. 116 [PubMed]
Wang J et al. (2001). SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport. American journal of physiology. Renal physiology. 280 [PubMed]
Webster MK, Goya L, Firestone GL. (1993). Immediate-early transcriptional regulation and rapid mRNA turnover of a putative serine/threonine protein kinase. The Journal of biological chemistry. 268 [PubMed]
Webster MK, Goya L, Ge Y, Maiyar AC, Firestone GL. (1993). Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum. Molecular and cellular biology. 13 [PubMed]
Wulff P et al. (2002). Impaired renal Na(+) retention in the sgk1-knockout mouse. The Journal of clinical investigation. 110 [PubMed]
Yee KM, Lim PO, Ogston SA, Struthers AD. (2000). Effect of phenylephrine with and without atropine on QT dispersion in healthy normotensive men. The American journal of cardiology. 85 [PubMed]