Ben-Shalom R et al. (2017). Opposing Effects on NaV1.2 Function Underlie Differences Between SCN2A Variants Observed in Individuals With Autism Spectrum Disorder or Infantile Seizures. Biological psychiatry. 82 [PubMed]

• Pyramidal neurons with mutated SCN2A gene (Nav1.2) (Ben-Shalom et al 2017) [Model]

Ferguson KA, Huh CY, Amilhon B, Williams S, Skinner FK. (2013). Experimentally constrained CA1 fast-firing parvalbumin-positive interneuron network models exhibit sharp transitions into coherent high frequency rhythms. Frontiers in computational neuroscience. 7 [PubMed]

• CA1 PV+ fast-firing hippocampal interneuron (Ferguson et al. 2013) [Model]

Lee SH et al. (2014). Parvalbumin-positive basket cells differentiate among hippocampal pyramidal cells. Neuron. 82 [PubMed]

• Parvalbumin-positive basket cells differentiate among hippocampal pyramidal cells (Lee et al. 2014) [Model]

Royeck M et al. (2008). Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons. Journal of neurophysiology. 100 [PubMed]

• Axonal NaV1.6 Sodium Channels in AP Initiation of CA1 Pyramidal Neurons (Royeck et al. 2008) [Model]

Spratt PWE et al. (2021). Paradoxical hyperexcitability from NaV1.2 sodium channel loss in neocortical pyramidal cells Cell reports. 36 [PubMed]

• Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al 2021) [Model]

Thomas EA, Reid CA, Berkovic SF, Petrou S. (2009). Prediction by modeling that epilepsy may be caused by very small functional changes in ion channels. Archives of neurology. 66 [PubMed]

• Epilepsy may be caused by very small functional changes in ion channels (Thomas et al. 2009) [Model]

Thomas EA, Reid CA, Petrou S. (2010). Mossy fiber sprouting interacts with sodium channel mutations to increase dentate gyrus excitability. Epilepsia. 51 [PubMed]

• Na channel mutations in the dentate gyrus (Thomas et al. 2009) [Model]

Wimmer VC et al. (2010). Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus. The Journal of clinical investigation. 120 [PubMed]

• Complex CA1-neuron to study AP initiation (Wimmer et al. 2010) [Model]