Tanskanen AJ, Greenstein JL, O'Rourke B, Winslow RL. (2005). The role of stochastic and modal gating of cardiac L-type Ca2+ channels on early after-depolarizations. Biophysical journal. 88 [PubMed]

See more from authors: Tanskanen AJ · Greenstein JL · O'Rourke B · Winslow RL

References and models cited by this paper

Anderson ME. (2004). Calmodulin kinase and L-type calcium channels; a recipe for arrhythmias? Trends in cardiovascular medicine. 14 [PubMed]

Chen X et al. (2002). L-type Ca2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices. Circulation research. 91 [PubMed]

Chen-Izu Y et al. (2000). G(i)-dependent localization of beta(2)-adrenergic receptor signaling to L-type Ca(2+) channels. Biophysical journal. 79 [PubMed]

Chow CC, White JA. (1996). Spontaneous action potentials due to channel fluctuations. Biophysical journal. 71 [PubMed]

De Ferrari GM, Viola MC, D'Amato E, Antolini R, Forti S. (1995). Distinct patterns of calcium transients during early and delayed afterdepolarizations induced by isoproterenol in ventricular myocytes. Circulation. 91 [PubMed]

De Jongh KS et al. (1996). Specific phosphorylation of a site in the full-length form of the alpha 1 subunit of the cardiac L-type calcium channel by adenosine 3',5'-cyclic monophosphate-dependent protein kinase. Biochemistry. 35 [PubMed]

Dzhura I, Wu Y, Colbran RJ, Balser JR, Anderson ME. (2000). Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels. Nature cell biology. 2 [PubMed]

Engeln-Mullges G, Uhlig F. (1996). Numerical Algorithms with C.

Erxleben C et al. (2003). Modulation of cardiac Ca(V)1.2 channels by dihydropyridine and phosphatase inhibitor requires Ser-1142 in the domain III pore loop. Proceedings of the National Academy of Sciences of the United States of America. 100 [PubMed]

Feller W. (1968). An Introduction to Probability Theory and Its Applications.

Gao T et al. (1997). cAMP-dependent regulation of cardiac L-type Ca2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits. Neuron. 19 [PubMed]

Greenstein JL, Tanskanen AJ, Winslow RL. (2004). Modeling the actions of beta-adrenergic signaling on excitation--contraction coupling processes. Annals of the New York Academy of Sciences. 1015 [PubMed]

Greenstein JL, Winslow RL. (2002). An integrative model of the cardiac ventricular myocyte incorporating local control of Ca2+ release. Biophysical journal. 83 [PubMed]

Greenstein JL, Wu R, Po S, Tomaselli GF, Winslow RL. (2000). Role of the calcium-independent transient outward current I(to1) in shaping action potential morphology and duration. Circulation research. 87 [PubMed]

Handrock R et al. (1998). Single-channel properties of L-type calcium channels from failing human ventricle. Cardiovascular research. 37 [PubMed]

Heath BM, Terrar DA. (2000). Protein kinase C enhances the rapidly activating delayed rectifier potassium current, IKr, through a reduction in C-type inactivation in guinea-pig ventricular myocytes. The Journal of physiology. 522 Pt 3 [PubMed]

Herzig S, Patil P, Neumann J, Staschen CM, Yue DT. (1993). Mechanisms of beta-adrenergic stimulation of cardiac Ca2+ channels revealed by discrete-time Markov analysis of slow gating. Biophysical journal. 65 [PubMed]

Hobai IA, O'Rourke B. (2001). Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure. Circulation. 103 [PubMed]

Imredy JP, Yue DT. (1994). Mechanism of Ca(2+)-sensitive inactivation of L-type Ca2+ channels. Neuron. 12 [PubMed]

Jafri MS, Rice JJ, Winslow RL. (1998). Cardiac Ca2+ dynamics: the roles of ryanodine receptor adaptation and sarcoplasmic reticulum load. Biophysical journal. 74 [PubMed]

January CT, Riddle JM. (1989). Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current. Circulation research. 64 [PubMed]

January CT, Riddle JM, Salata JJ. (1988). A model for early afterdepolarizations: induction with the Ca2+ channel agonist Bay K 8644. Circulation research. 62 [PubMed]

Josephson IR, Guia A, Lakatta EG, Stern MD. (2002). Modulation of the conductance of unitary cardiac L-type Ca(2+) channels by conditioning voltage and divalent ions. Biophysical journal. 83 [PubMed]

Kathöfer S et al. (2000). Functional coupling of human beta 3-adrenoreceptors to the KvLQT1/MinK potassium channel. The Journal of biological chemistry. 275 [PubMed]

Keizer J, Smith GD, Ponce-Dawson S, Pearson JE. (1998). Saltatory propagation of Ca2+ waves by Ca2+ sparks. Biophysical journal. 75 [PubMed]

Kääb S et al. (1996). Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure. Circulation research. 78 [PubMed]

Marban E, Robinson SW, Wier WG. (1986). Mechanisms of arrhythmogenic delayed and early afterdepolarizations in ferret ventricular muscle. The Journal of clinical investigation. 78 [PubMed]

Matsumoto M. (1998). Mersenne Twister: A 623-dimensionally equidistributed uniform pseudo-random number generator ACM Trans Model Comput Sim. 8

Mazhari R, Greenstein JL, Winslow RL, Marbán E, Nuss HB. (2001). Molecular interactions between two long-QT syndrome gene products, HERG and KCNE2, rationalized by in vitro and in silico analysis. Circulation research. 89 [PubMed]

Mazur A, Roden DM, Anderson ME. (1999). Systemic administration of calmodulin antagonist W-7 or protein kinase A inhibitor H-8 prevents torsade de pointes in rabbits. Circulation. 100 [PubMed]

McDonald TF, Cavalié A, Trautwein W, Pelzer D. (1986). Voltage-dependent properties of macroscopic and elementary calcium channel currents in guinea pig ventricular myocytes. Pflugers Archiv : European journal of physiology. 406 [PubMed]

Nuss HB, Kääb S, Kass DA, Tomaselli GF, Marbán E. (1999). Cellular basis of ventricular arrhythmias and abnormal automaticity in heart failure. The American journal of physiology. 277 [PubMed]

Percival DB, Walden AT. (1993). Spectral Analysis for Physical Applications.

Priori SG, Corr PB. (1990). Mechanisms underlying early and delayed afterdepolarizations induced by catecholamines. The American journal of physiology. 258 [PubMed]

Rice JJ, Jafri MS, Winslow RL. (1999). Modeling gain and gradedness of Ca2+ release in the functional unit of the cardiac diadic space. Biophysical journal. 77 [PubMed]

Roden DM. (1993). Early after-depolarizations and torsade de pointes: implications for the control of cardiac arrhythmias by prolonging repolarization. European heart journal. 14 Suppl H [PubMed]

Rose WC, Balke CW, Wier WG, Marban E. (1992). Macroscopic and unitary properties of physiological ion flux through L-type Ca2+ channels in guinea-pig heart cells. The Journal of physiology. 456 [PubMed]

Schröder F et al. (1998). Increased availability and open probability of single L-type calcium channels from failing compared with nonfailing human ventricle. Circulation. 98 [PubMed]

Shannon TR, Ginsburg KS, Bers DM. (2000). Reverse mode of the sarcoplasmic reticulum calcium pump and load-dependent cytosolic calcium decline in voltage-clamped cardiac ventricular myocytes. Biophysical journal. 78 [PubMed]

Simmerman HK, Jones LR. (1998). Phospholamban: protein structure, mechanism of action, and role in cardiac function. Physiological reviews. 78 [PubMed]

Stern MD, Lakatta EG, Josephson IR, Guia A. (2002). Modulation of the gating of unitary cardiac L-type Ca(2+) channels by conditioning voltage and divalent ions. Biophys J. 83

Tsien RW et al. (1986). Mechanisms of calcium channel modulation by beta-adrenergic agents and dihydropyridine calcium agonists. Journal of molecular and cellular cardiology. 18 [PubMed]

Tsien RW, Hess P, Lansman JB. (2004). Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists. Nature. 311

Volders PG et al. (1997). Similarities between early and delayed afterdepolarizations induced by isoproterenol in canine ventricular myocytes. Cardiovascular research. 34 [PubMed]

White JA, Klink R, Alonso A, Kay AR. (1998). Noise from voltage-gated ion channels may influence neuronal dynamics in the entorhinal cortex. Journal of neurophysiology. 80 [PubMed]

White JA, Rubinstein JT, Kay AR. (2000). Channel noise in neurons. Trends in neurosciences. 23 [PubMed]

Winslow RL, Rice J, Jafri S, Marbán E, O'Rourke B. (1999). Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, II: model studies. Circulation research. 84 [PubMed]

Wu Y et al. (2002). Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy. Circulation. 106 [PubMed]

Yoshida A, Takahashi M, Nishimura S, Takeshima H, Kokubun S. (1992). Cyclic AMP-dependent phosphorylation and regulation of the cardiac dihydropyridine-sensitive Ca channel. FEBS letters. 309 [PubMed]

Yue DT, Herzig S, Marban E. (1990). Beta-adrenergic stimulation of calcium channels occurs by potentiation of high-activity gating modes. Proceedings of the National Academy of Sciences of the United States of America. 87 [PubMed]

Zaniboni M, Pollard AE, Yang L, Spitzer KW. (2000). Beat-to-beat repolarization variability in ventricular myocytes and its suppression by electrical coupling. American journal of physiology. Heart and circulatory physiology. 278 [PubMed]

Zeng J, Rudy Y. (1995). Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence. Biophysical journal. 68 [PubMed]

Zhou JT, Zheng LR, Liu WY. (1992). Role of early afterdepolarization in familial long QTU syndrome and torsade de pointes. Pacing and clinical electrophysiology : PACE. 15 [PubMed]

References and models that cite this paper

Greenstein JL, Hinch R, Winslow RL. (2006). Mechanisms of excitation-contraction coupling in an integrative model of the cardiac ventricular myocyte. Biophysical journal. 90 [PubMed]

Winslow RL, Cortassa S, Greenstein JL. (2005). Using models of the myocyte for functional interpretation of cardiac proteomic data. The Journal of physiology. 563 [PubMed]

This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.