Coskren PJ et al. (2015). Functional consequences of age-related morphologic changes to pyramidal neurons of the rhesus monkey prefrontal cortex. Journal of computational neuroscience. 38 [PubMed]

See more from authors: Coskren PJ · Luebke JI · Kabaso D · Wearne SL · Yadav A · Rumbell T · Hof PR · Weaver CM

References and models cited by this paper

Amatrudo JM et al. (2012). Influence of highly distinctive structural properties on the excitability of pyramidal neurons in monkey visual and prefrontal cortices. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32 [PubMed]

Antic SD, Zhou WL, Moore AR, Short SM, Ikonomu KD. (2010). The decade of the dendritic NMDA spike. Journal of neuroscience research. 88 [PubMed]

Bai L et al. (2004). Changes in the expression of the NR2B subunit during aging in macaque monkeys. Neurobiology of aging. 25 [PubMed]

Betts LR, Sekuler AB, Bennett PJ. (2007). The effects of aging on orientation discrimination. Vision research. 47 [PubMed]

Blalock EM, Porter NM, Landfield PW. (1999). Decreased G-protein-mediated regulation and shift in calcium channel types with age in hippocampal cultures. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19 [PubMed]

Branco T, Häusser M. (2010). The single dendritic branch as a fundamental functional unit in the nervous system. Current opinion in neurobiology. 20 [PubMed]

Cannon RC, Turner DA, Pyapali GK, Wheal HV. (1998). An on-line archive of reconstructed hippocampal neurons. Journal of neuroscience methods. 84 [PubMed]

Carnevale NT. (). IClamp experiment with custom initialization. http://www.neuron.yale.edu/ftp/ted/neuron/iclamp_experiment_ with_custom_init.zip.

Carnevale NT, Tsai KY, Claiborne BJ, Brown TH. (1994). Efficient mapping from neuroanatomical to electronic space Network. 5

Carnevale NT, Tsai KY, Claiborne BJ, Brown TH. (1997). Comparative electrotonic analysis of three classes of rat hippocampal neurons. Journal of neurophysiology. 78 [PubMed]

Chang YM, Luebke JI. (2007). Electrophysiological diversity of layer 5 pyramidal cells in the prefrontal cortex of the rhesus monkey: in vitro slice studies. Journal of neurophysiology. 98 [PubMed]

Chang YM, Rosene DL, Killiany RJ, Mangiamele LA, Luebke JI. (2005). Increased action potential firing rates of layer 2/3 pyramidal cells in the prefrontal cortex are significantly related to cognitive performance in aged monkeys. Cerebral cortex (New York, N.Y. : 1991). 15 [PubMed]

Claiborne BJ, Brown TH, Mainen ZF, Zador AM. (1992). Hebbian computations in hippocampal dendrites and spines Single Neuron Computation.

Constantinidis C, Franowicz MN, Goldman-Rakic PS. (2001). Coding specificity in cortical microcircuits: a multiple-electrode analysis of primate prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. 21 [PubMed]

Dickstein DL et al. (2007). Changes in the structural complexity of the aged brain. Aging cell. 6 [PubMed]

Dickstein DL, Weaver CM, Luebke JI, Hof PR. (2013). Dendritic spine changes associated with normal aging. Neuroscience. 251 [PubMed]

Duan H et al. (2003). Age-related dendritic and spine changes in corticocortically projecting neurons in macaque monkeys. Cerebral cortex (New York, N.Y. : 1991). 13 [PubMed]

Dumitriu D et al. (2010). Selective changes in thin spine density and morphology in monkey prefrontal cortex correlate with aging-related cognitive impairment. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30 [PubMed]

Edwards FA, Konnerth A, Sakmann B, Takahashi T. (1989). A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system. Pflugers Archiv : European journal of physiology. 414 [PubMed]

Euler T, Denk W. (2001). Dendritic processing. Current opinion in neurobiology. 11 [PubMed]

Faber ES, Sah P. (2003). Calcium-activated potassium channels: multiple contributions to neuronal function. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 9 [PubMed]

Foster TC. (2007). Calcium homeostasis and modulation of synaptic plasticity in the aged brain. Aging cell. 6 [PubMed]

Fristoe NM, Salthouse TA, Woodard JL. (1997). Examination of age-related deficits on the Wisconsin Card Sorting Test. Neuropsychology. 11 [PubMed]

Frolkis VV, Martynenko OA, Timchenko AN. (1989). Age-related changes in the function of somatic membrane potassium channels of neurons in the mollusc Lymnaea stagnalis. Mechanisms of ageing and development. 47 [PubMed]

Fu Y, Yu S, Ma Y, Wang Y, Zhou Y. (2013). Functional degradation of the primary visual cortex during early senescence in rhesus monkeys. Cerebral cortex (New York, N.Y. : 1991). 23 [PubMed]

Funahashi S, Bruce CJ, Goldman-Rakic PS. (1989). Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex. Journal of neurophysiology. 61 [PubMed]

Funahashi S, Bruce CJ, Goldman-Rakic PS. (1990). Visuospatial coding in primate prefrontal neurons revealed by oculomotor paradigms. Journal of neurophysiology. 63 [PubMed]

Gallagher M, Rapp PR. (1997). The use of animal models to study the effects of aging on cognition. Annual review of psychology. 48 [PubMed]

Geisser S, Greenhouse SW. (1958). An extension of Box's result on the use of the F distribution in multivariate analysis Annals of Mathematical Statistics. 29

Girden ER. (1992). ANOVA: repeated measures.

Goldman-Rakic PS. (1995). Cellular basis of working memory. Neuron. 14 [PubMed]

Hara Y, Rapp PR, Morrison JH. (2012). Neuronal and morphological bases of cognitive decline in aged rhesus monkeys. Age (Dordrecht, Netherlands). 34 [PubMed]

Herndon JG, Moss MB, Rosene DL, Killiany RJ. (1997). Patterns of cognitive decline in aged rhesus monkeys. Behavioural brain research. 87 [PubMed]

Hines ML, Carnevale NT. (2006). The NEURON Book.

Hines ML, Morse T, Migliore M, Carnevale NT, Shepherd GM. (2004). ModelDB: A Database to Support Computational Neuroscience. Journal of computational neuroscience. 17 [PubMed]

Hodgkin AL. (1948). The local electric changes associated with repetitive action in a non-medullated axon. The Journal of physiology. 107 [PubMed]

Hof PR et al. (2002). Age-related changes in GluR2 and NMDAR1 glutamate receptor subunit protein immunoreactivity in corticocortically projecting neurons in macaque and patas monkeys. Brain research. 928 [PubMed]

Hof PR, Morrison JH. (2004). The aging brain: morphomolecular senescence of cortical circuits. Trends in neurosciences. 27 [PubMed]

Häusser M, Mel B. (2003). Dendrites: bug or feature? Current opinion in neurobiology. 13 [PubMed]

Kabaso D, Coskren PJ, Henry BI, Hof PR, Wearne SL. (2009). The electrotonic structure of pyramidal neurons contributing to prefrontal cortical circuits in macaque monkeys is significantly altered in aging. Cerebral cortex (New York, N.Y. : 1991). 19 [PubMed]

Krichmar JL, Nasuto SJ, Scorcioni R, Washington SD, Ascoli GA. (2002). Effects of dendritic morphology on CA3 pyramidal cell electrophysiology: a simulation study. Brain research. 941 [PubMed]

London M, Häusser M. (2005). Dendritic computation. Annual review of neuroscience. 28 [PubMed]

Losonczy A, Makara JK, Magee JC. (2008). Compartmentalized dendritic plasticity and input feature storage in neurons. Nature. 452 [PubMed]

Luebke J, Barbas H, Peters A. (2010). Effects of normal aging on prefrontal area 46 in the rhesus monkey. Brain research reviews. 62 [PubMed]

Luebke JI, Amatrudo JM. (2012). Age-related increase of sI(AHP) in prefrontal pyramidal cells of monkeys: relationship to cognition. Neurobiology of aging. 33 [PubMed]

Luebke JI, Chang YM, Moore TL, Rosene DL. (2004). Normal aging results in decreased synaptic excitation and increased synaptic inhibition of layer 2/3 pyramidal cells in the monkey prefrontal cortex. Neuroscience. 125 [PubMed]

Luebke JI, Hof PR, Weaver CM, Rumbell T, Draguljic D. (2014). Automatic fitness function selection for compartment model optimization BMC Neuroscience. 15(s1)

Magee JC. (2000). Dendritic integration of excitatory synaptic input. Nature reviews. Neuroscience. 1 [PubMed]

Mainen ZF, Joerges J, Huguenard JR, Sejnowski TJ. (1995). A model of spike initiation in neocortical pyramidal neurons. Neuron. 15 [PubMed]

Mainen ZF, Sejnowski TJ. (1996). Influence of dendritic structure on firing pattern in model neocortical neurons. Nature. 382 [PubMed]

Major G, Larkman AU, Stratford KJ, Mason AJR, Jack JJB. (1989). The modelling of pyramidal neurones in the visual cortex The Computing Neuron.

Marder E, Goaillard JM. (2006). Variability, compensation and homeostasis in neuron and network function. Nature reviews. Neuroscience. 7 [PubMed]

Migliore M, Shepherd GM. (2002). Emerging rules for the distributions of active dendritic conductances. Nature reviews. Neuroscience. 3 [PubMed]

Moore TL, Killiany RJ, Herndon JG, Rosene DL, Moss MB. (2003). Impairment in abstraction and set shifting in aged rhesus monkeys. Neurobiology of aging. 24 [PubMed]

Morrison JH, Baxter MG. (2012). The ageing cortical synapse: hallmarks and implications for cognitive decline. Nature reviews. Neuroscience. 13 [PubMed]

Niesen CE, Baskys A, Carlen PL. (1988). Reversed ethanol effects on potassium conductances in aged hippocampal dentate granule neurons. Brain research. 445 [PubMed]

Nörenberg A, Hu H, Vida I, Bartos M, Jonas P. (2010). Distinct nonuniform cable properties optimize rapid and efficient activation of fast-spiking GABAergic interneurons. Proceedings of the National Academy of Sciences of the United States of America. 107 [PubMed]

Oh MM, Oliveira FA, Waters J, Disterhoft JF. (2013). Altered calcium metabolism in aging CA1 hippocampal pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33 [PubMed]

Page TL et al. (2002). Morphological alterations in neurons forming corticocortical projections in the neocortex of aged Patas monkeys. Neuroscience letters. 317 [PubMed]

Peters A. (2002). Structural changes that occur during normal aging of primate cerebral hemispheres. Neuroscience and biobehavioral reviews. 26 [PubMed]

Porter NM, Thibault O, Thibault V, Chen KC, Landfield PW. (1997). Calcium channel density and hippocampal cell death with age in long-term culture. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17 [PubMed]

Rinzel J, Ermentrout B. (1998). Analysis of neural excitability and oscillations. Methods In Neuronal Modeling 2nd Edition.

Rodriguez A, Ehlenberger DB, Dickstein DL, Hof PR, Wearne SL. (2008). Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images. PloS one. 3 [PubMed]

Rodriguez A, Ehlenberger DB, Hof PR, Wearne SL. (2006). Rayburst sampling, an algorithm for automated three-dimensional shape analysis from laser scanning microscopy images. Nature protocols. 1 [PubMed]

Rodriguez A, Ehlenberger DB, Hof PR, Wearne SL. (2009). Three-dimensional neuron tracing by voxel scooping. Journal of neuroscience methods. 184 [PubMed]

Ross WN. (2012). Understanding calcium waves and sparks in central neurons. Nature reviews. Neuroscience. 13 [PubMed]

Schaefer AT, Larkum ME, Sakmann B, Roth A. (2003). Coincidence detection in pyramidal neurons is tuned by their dendritic branching pattern. Journal of neurophysiology. 89 [PubMed]

Schmolesky MT, Wang Y, Creel DJ, Leventhal AG. (2000). Abnormal retinotopic organization of the dorsal lateral geniculate nucleus of the tyrosinase-negative albino cat. The Journal of comparative neurology. 427 [PubMed]

Schneider CA, Rasband WS, Eliceiri KW. (2012). NIH Image to ImageJ: 25 years of image analysis. Nature methods. 9 [PubMed]

Skinner FK. (2013). Moving beyond Type I and Type II neuron types. F1000Research. 2 [PubMed]

Stuart G, Spruston N. (1998). Determinants of voltage attenuation in neocortical pyramidal neuron dendrites. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18 [PubMed]

Thibault O, Gant JC, Landfield PW. (2007). Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store. Aging cell. 6 [PubMed]

Thibault O, Hadley R, Landfield PW. (2001). Elevated postsynaptic [Ca2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 21 [PubMed]

Thibault O, Landfield PW. (1996). Increase in single L-type calcium channels in hippocampal neurons during aging. Science (New York, N.Y.). 272 [PubMed]

Thurbon D, Lüscher HR, Hofstetter T, Redman SJ. (1998). Passive electrical properties of ventral horn neurons in rat spinal cord slices. Journal of neurophysiology. 79 [PubMed]

Traub RD, Buhl EH, Gloveli T, Whittington MA. (2003). Fast rhythmic bursting can be induced in layer 2/3 cortical neurons by enhancing persistent Na+ conductance or by blocking BK channels. Journal of neurophysiology. 89 [PubMed]

Trevelyan AJ, Jack J. (2002). Detailed passive cable models of layer 2/3 pyramidal cells in rat visual cortex at different temperatures. The Journal of physiology. 539 [PubMed]

Vetter P, Roth A, Häusser M. (2001). Propagation of action potentials in dendrites depends on dendritic morphology. Journal of neurophysiology. 85 [PubMed]

Wang M et al. (2011). Neuronal basis of age-related working memory decline. Nature. 476 [PubMed]

Wearne SL et al. (2005). New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales. Neuroscience. 136 [PubMed]

Weaver CM, Wearne SL. (2008). Neuronal firing sensitivity to morphologic and active membrane parameters. PLoS computational biology. 4 [PubMed]

Wilson IA, Ikonen S, Gallagher M, Eichenbaum H, Tanila H. (2005). Age-associated alterations of hippocampal place cells are subregion specific. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

Zhang J et al. (2008). Spatial and temporal sensitivity degradation of primary visual cortical cells in senescent rhesus monkeys. The European journal of neuroscience. 28 [PubMed]

van Elburg RA, van Ooyen A. (2010). Impact of dendritic size and dendritic topology on burst firing in pyramidal cells. PLoS computational biology. 6 [PubMed]

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