Prescott SA, De Koninck Y. (2005). Integration time in a subset of spinal lamina I neurons is lengthened by sodium and calcium currents acting synergistically to prolong subthreshold depolarization. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

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References and models cited by this paper

Abeles M. (1982). Role of the cortical neuron: integrator or coincidence detector? Israel journal of medical sciences. 18 [PubMed]

Agrawal N, Hamam BN, Magistretti J, Alonso A, Ragsdale DS. (2001). Persistent sodium channel activity mediates subthreshold membrane potential oscillations and low-threshold spikes in rat entorhinal cortex layer V neurons. Neuroscience. 102 [PubMed]

Axmacher N, Miles R. (2004). Intrinsic cellular currents and the temporal precision of EPSP-action potential coupling in CA1 pyramidal cells. The Journal of physiology. 555 [PubMed]

Barry PH, Lynch JW. (1991). Liquid junction potentials and small cell effects in patch-clamp analysis. The Journal of membrane biology. 121 [PubMed]

Chéry N, Yu XH, de Koninck Y. (2000). Visualization of lamina I of the dorsal horn in live adult rat spinal cord slices. Journal of neuroscience methods. 96 [PubMed]

Chéry N, de Koninck Y. (1999). Junctional versus extrajunctional glycine and GABA(A) receptor-mediated IPSCs in identified lamina I neurons of the adult rat spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19 [PubMed]

Connors BW, Gutnick MJ. (1990). Intrinsic firing patterns of diverse neocortical neurons. Trends in neurosciences. 13 [PubMed]

Coull JA et al. (2003). Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain. Nature. 424 [PubMed]

Craig AD. (1994). Spinal and supraspinal processing of specific pain andtemperature Touch, temperature, and pain in health and disease.

Craig AD. (2000). The functional anatomy of lamina I and its role in post-stroke central pain. Progress in brain research. 129 [PubMed]

Crill WE. (1996). Persistent sodium current in mammalian central neurons. Annual review of physiology. 58 [PubMed]

Crill WE. (2003). Functional implications of dendritic voltage-dependent conductances. J Physiol Paris. 93

Crill WE, Schwindt PC, Oakley JC. (2002). Enhanced transmission of glutamate current flowing from the dendrite to the soma in rat neocortical layer 5 neurons. Novartis Foundation symposium. 241 [PubMed]

Deisz RA, Fortin G, Zieglgänsberger W. (1991). Voltage dependence of excitatory postsynaptic potentials of rat neocortical neurons. Journal of neurophysiology. 65 [PubMed]

Derjean D et al. (2003). Dynamic balance of metabotropic inputs causes dorsal horn neurons to switch functional states. Nature neuroscience. 6 [PubMed]

Destexhe A, Contreras D, Sejnowski TJ, Steriade M. (1994). A model of spindle rhythmicity in the isolated thalamic reticular nucleus. Journal of neurophysiology. 72 [PubMed]

Dodt HU, Frick A, Kampe K, Zieglgänsberger W. (1998). NMDA and AMPA receptors on neocortical neurons are differentially distributed. The European journal of neuroscience. 10 [PubMed]

Fleidervish IA, Gutnick MJ. (1996). Kinetics of slow inactivation of persistent sodium current in layer V neurons of mouse neocortical slices. Journal of neurophysiology. 76 [PubMed]

Fricker D, Miles R. (2000). EPSP amplification and the precision of spike timing in hippocampal neurons. Neuron. 28 [PubMed]

Furue H, Narikawa K, Kumamoto E, Yoshimura M. (1999). Responsiveness of rat substantia gelatinosa neurones to mechanical but not thermal stimuli revealed by in vivo patch-clamp recording. The Journal of physiology. 521 Pt 2 [PubMed]

Geijo-Barrientos E. (2000). Subthreshold inward membrane currents in guinea-pig frontal cortex neurons. Neuroscience. 95 [PubMed]

Gillessen T, Alzheimer C. (1997). Amplification of EPSPs by low Ni(2+)- and amiloride-sensitive Ca2+ channels in apical dendrites of rat CA1 pyramidal neurons. Journal of neurophysiology. 77 [PubMed]

González-Burgos G, Barrionuevo G. (2001). Voltage-gated sodium channels shape subthreshold EPSPs in layer 5 pyramidal neurons from rat prefrontal cortex. Journal of neurophysiology. 86 [PubMed]

Grudt TJ, Perl ER. (2002). Correlations between neuronal morphology and electrophysiological features in the rodent superficial dorsal horn. The Journal of physiology. 540 [PubMed]

Heinke B, Balzer E, Sandkühler J. (2004). Pre- and postsynaptic contributions of voltage-dependent Ca2+ channels to nociceptive transmission in rat spinal lamina I neurons. The European journal of neuroscience. 19 [PubMed]

Herzog RI, Cummins TR, Waxman SG. (2001). Persistent TTX-resistant Na+ current affects resting potential and response to depolarization in simulated spinal sensory neurons. Journal of neurophysiology. 86 [PubMed]

Higure Y, Katayama Y, Takeuchi K, Ohtubo Y, Yoshii K. (2003). Lucifer Yellow slows voltage-gated Na+ current inactivation in a light-dependent manner in mice. The Journal of physiology. 550 [PubMed]

Hines ML, Carnevale NT. (1997). The NEURON simulation environment. Neural computation. 9 [PubMed]

Ikeda H, Heinke B, Ruscheweyh R, Sandkühler J. (2003). Synaptic plasticity in spinal lamina I projection neurons that mediate hyperalgesia. Science (New York, N.Y.). 299 [PubMed]

Jo YH, Stoeckel ME, Schlichter R. (1998). Electrophysiological properties of cultured neonatal rat dorsal horn neurons containing GABA and met-enkephalin-like immunoreactivity. Journal of neurophysiology. 79 [PubMed]

Kay AR, Wong RK. (1987). Calcium current activation kinetics in isolated pyramidal neurones of the Ca1 region of the mature guinea-pig hippocampus. The Journal of physiology. 392 [PubMed]

König P, Engel AK, Singer W. (1996). Integrator or coincidence detector? The role of the cortical neuron revisited. Trends in neurosciences. 19 [PubMed]

Lee JH, Gomora JC, Cribbs LL, Perez-Reyes E. (1999). Nickel block of three cloned T-type calcium channels: low concentrations selectively block alpha1H. Biophysical journal. 77 [PubMed]

Lee RH, Heckman CJ. (2001). Essential role of a fast persistent inward current in action potential initiation and control of rhythmic firing. Journal of neurophysiology. 85 [PubMed]

Light AR. (1992). The initial processing of pain and its descending control:spinal and trigeminal systems.

Lipowsky R, Gillessen T, Alzheimer C. (1996). Dendritic Na+ channels amplify EPSPs in hippocampal CA1 pyramidal cells. Journal of neurophysiology. 76 [PubMed]

Llinás RR. (1988). The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function. Science (New York, N.Y.). 242 [PubMed]

Lopez-Garcia JA, King AE. (1994). Membrane properties of physiologically classified rat dorsal horn neurons in vitro: correlation with cutaneous sensory afferent input. The European journal of neuroscience. 6 [PubMed]

Magee JC. (2000). Dendritic integration of excitatory synaptic input. Nature reviews. Neuroscience. 1 [PubMed]

Magee JC, Carruth M. (1999). Dendritic voltage-gated ion channels regulate the action potential firing mode of hippocampal CA1 pyramidal neurons. Journal of neurophysiology. 82 [PubMed]

Mainen ZF, Joerges J, Huguenard JR, Sejnowski TJ. (1995). A model of spike initiation in neocortical pyramidal neurons. Neuron. 15 [PubMed]

Morisset V, Nagy F. (1998). Nociceptive integration in the rat spinal cord: role of non-linear membrane properties of deep dorsal horn neurons. The European journal of neuroscience. 10 [PubMed]

Morisset V, Nagy F. (1999). Ionic basis for plateau potentials in deep dorsal horn neurons of the rat spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19 [PubMed]

Paternain AV, Morales M, Lerma J. (1995). Selective antagonism of AMPA receptors unmasks kainate receptor-mediated responses in hippocampal neurons. Neuron. 14 [PubMed]

Perl ER. (1984). Pain and nociception Sensory processes.

Pouille F, Scanziani M. (2001). Enforcement of temporal fidelity in pyramidal cells by somatic feed-forward inhibition. Science (New York, N.Y.). 293 [PubMed]

Prescott SA, De Koninck Y. (2002). Four cell types with distinctive membrane properties and morphologies in lamina I of the spinal dorsal horn of the adult rat. The Journal of physiology. 539 [PubMed]

Rudolph M, Destexhe A. (2003). Tuning neocortical pyramidal neurons between integrators and coincidence detectors. Journal of computational neuroscience. 14 [PubMed]

Ruscheweyh R, Ikeda H, Heinke B, Sandkühler J. (2004). Distinctive membrane and discharge properties of rat spinal lamina I projection neurones in vitro. The Journal of physiology. 555 [PubMed]

Ruscheweyh R, Sandkühler J. (2002). Lamina-specific membrane and discharge properties of rat spinal dorsal horn neurones in vitro. The Journal of physiology. 541 [PubMed]

Russo RE, Hounsgaard J. (1999). Dynamics of intrinsic electrophysiological properties in spinal cord neurones. Progress in biophysics and molecular biology. 72 [PubMed]

Safronov BV. (1999). Spatial distribution of NA+ and K+ channels in spinal dorsal horn neurones: role of the soma, axon and dendrites in spike generation. Progress in neurobiology. 59 [PubMed]

Safronov BV, Wolff M, Vogel W. (1997). Functional distribution of three types of Na+ channel on soma and processes of dorsal horn neurones of rat spinal cord. The Journal of physiology. 503 ( Pt 2) [PubMed]

Schneider SP. (2003). Spike frequency adaptation and signaling properties of identified neurons in rodent deep spinal dorsal horn. Journal of neurophysiology. 90 [PubMed]

Schwindt PC, Spain WJ, Crill WE. (1992). Effects of intracellular calcium chelation on voltage-dependent and calcium-dependent currents in cat neocortical neurons. Neuroscience. 47 [PubMed]

Staley KJ, Otis TS, Mody I. (1992). Membrane properties of dentate gyrus granule cells: comparison of sharp microelectrode and whole-cell recordings. Journal of neurophysiology. 67 [PubMed]

Stuart G, Sakmann B. (1995). Amplification of EPSPs by axosomatic sodium channels in neocortical pyramidal neurons. Neuron. 15 [PubMed]

Thomson AM, West DC, Headley PM. (1989). Membrane Characteristics and Synaptic Responsiveness of Superficial Dorsal Horn Neurons in a Slice Preparation of Adult Rat Spinal Cord. The European journal of neuroscience. 1 [PubMed]

Traub RD, Miles R. (1991). Neuronal Networks Of The Hippocampus.

Urban NN, Henze DA, Barrionuevo G. (1998). Amplification of perforant-path EPSPs in CA3 pyramidal cells by LVA calcium and sodium channels. Journal of neurophysiology. 80 [PubMed]

Willis WD. (1985). The pain system. The neural basis of nociceptive transmission in the mammalian nervous system. Pain and headache. 8 [PubMed]

Yoshimura M, Jessell TM. (1989). Membrane properties of rat substantia gelatinosa neurons in vitro. Journal of neurophysiology. 62 [PubMed]

Zhang L et al. (1994). Whole-cell recording of the Ca(2+)-dependent slow afterhyperpolarization in hippocampal neurones: effects of internally applied anions. Pflugers Archiv : European journal of physiology. 426 [PubMed]

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Kuo JJ, Lee RH, Zhang L, Heckman CJ. (2006). Essential role of the persistent sodium current in spike initiation during slowly rising inputs in mouse spinal neurones. The Journal of physiology. 574 [PubMed]

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