A single compartment model reproduces the firing rate maps of place, grid, and boundary cells by receiving inhibitory inputs from theta cells. The theta cell spike trains are modulated by the rat's movement velocity in such a way that phase interference among their burst pattern creates spatial envelope function which simulate the firing rate maps.
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Hippocampus CA1 pyramidal GLU cell; Hippocampus CA3 pyramidal GLU cell; Entorhinal cortex stellate cell
Currents: I Na,p
Model Concept(s): Synchronization; Envelope synthesis; Grid cell; Place cell/field
Simulation Environment: NEURON; MATLAB
Implementer(s): Blair, Hugh T.
References:
Welday AC, Shlifer IG, Bloom ML, Zhang K, Blair HT. (2011). Cosine directional tuning of theta cell burst frequencies: evidence for spatial coding by oscillatory interference. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31 [PubMed]