Fast sodium channel gating in mossy fiber axons (Schmidt-Hieber et al. 2010)


Schmidt-Hieber C, Bischofberger J. (2010). Fast sodium channel gating supports localized and efficient axonal action potential initiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30 [PubMed]

See more from authors: Schmidt-Hieber C · Bischofberger J

References and models cited by this paper

Alle H, Roth A, Geiger JR. (2009). Energy-efficient action potentials in hippocampal mossy fibers. Science (New York, N.Y.). 325 [PubMed]

Attwell D, Gibb A. (2005). Neuroenergetics and the kinetic design of excitatory synapses. Nature reviews. Neuroscience. 6 [PubMed]

Attwell D, Laughlin SB. (2001). An energy budget for signaling in the grey matter of the brain. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 21 [PubMed]

Baranauskas G, Martina M. (2006). Sodium currents activate without a Hodgkin-and-Huxley-type delay in central mammalian neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26 [PubMed]

Bischofberger J, Geiger JR, Jonas P. (2002). Timing and efficacy of Ca2+ channel activation in hippocampal mossy fiber boutons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 22 [PubMed]

Buhl EH, Halasy K, Somogyi P. (1994). Diverse sources of hippocampal unitary inhibitory postsynaptic potentials and the number of synaptic release sites. Nature. 368 [PubMed]

Buhl EH et al. (1994). Physiological properties of anatomically identified axo-axonic cells in the rat hippocampus. Journal of neurophysiology. 71 [PubMed]

Carter BC, Bean BP. (2009). Sodium entry during action potentials of mammalian neurons: incomplete inactivation and reduced metabolic efficiency in fast-spiking neurons. Neuron. 64 [PubMed]

Chanda B, Asamoah OK, Bezanilla F. (2004). Coupling interactions between voltage sensors of the sodium channel as revealed by site-specific measurements. The Journal of general physiology. 123 [PubMed]

Colbert CM, Pan E. (2002). Ion channel properties underlying axonal action potential initiation in pyramidal neurons. Nature neuroscience. 5 [PubMed]

Colquhoun D, Hawkes AG. (1977). Relaxation and fluctuations of membrane currents that flow through drug-operated channels. Proceedings of the Royal Society of London. Series B, Biological sciences. 199 [PubMed]

Engel D, Jonas P. (2005). Presynaptic action potential amplification by voltage-gated Na+ channels in hippocampal mossy fiber boutons. Neuron. 45 [PubMed]

Fleidervish IA, Lasser-Ross N, Gutnick MJ, Ross WN. (2010). Na+ imaging reveals little difference in action potential-evoked Na+ influx between axon and soma. Nature neuroscience. 13 [PubMed]

Geiger JR et al. (2002). Patch-clamp recording in brain slices with improved slicer technology. Pflugers Archiv : European journal of physiology. 443 [PubMed]

HODGKIN AL, HUXLEY AF. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. The Journal of physiology. 117 [PubMed]

Han ZS, Buhl EH, Lörinczi Z, Somogyi P. (1993). A high degree of spatial selectivity in the axonal and dendritic domains of physiologically identified local-circuit neurons in the dentate gyrus of the rat hippocampus. The European journal of neuroscience. 5 [PubMed]

Hines ML, Carnevale NT. (2006). The NEURON Book.

Hu W et al. (2009). Distinct contributions of Na(v)1.6 and Na(v)1.2 in action potential initiation and backpropagation. Nature neuroscience. 12 [PubMed]

Isom LL et al. (1992). Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel. Science (New York, N.Y.). 256 [PubMed]

Keynes RD, Rojas E. (1976). The temporal and steady-state relationships between activation of the sodium conductance and movement of the gating particles in the squid giant axon. The Journal of physiology. 255 [PubMed]

Kole MH et al. (2008). Action potential generation requires a high sodium channel density in the axon initial segment. Nature neuroscience. 11 [PubMed]

Kole MH, Letzkus JJ, Stuart GJ. (2007). Axon initial segment Kv1 channels control axonal action potential waveform and synaptic efficacy. Neuron. 55 [PubMed]

Kress GJ, Dowling MJ, Eisenman LN, Mennerick S. (2010). Axonal sodium channel distribution shapes the depolarized action potential threshold of dentate granule neurons. Hippocampus. 20 [PubMed]

Kress GJ, Dowling MJ, Meeks JP, Mennerick S. (2008). High threshold, proximal initiation, and slow conduction velocity of action potentials in dentate granule neuron mossy fibers. Journal of neurophysiology. 100 [PubMed]

Lorincz A, Nusser Z. (2010). Molecular identity of dendritic voltage-gated sodium channels. Science (New York, N.Y.). 328 [PubMed]

Mainen ZF, Joerges J, Huguenard JR, Sejnowski TJ. (1995). A model of spike initiation in neocortical pyramidal neurons. Neuron. 15 [PubMed]

Martina M, Jonas P. (1997). Functional differences in Na+ channel gating between fast-spiking interneurones and principal neurones of rat hippocampus. The Journal of physiology. 505 ( Pt 3) [PubMed]

Morgan K et al. (2000). beta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics. Proceedings of the National Academy of Sciences of the United States of America. 97 [PubMed]

Oxford GS. (1981). Some kinetic and steady-state properties of sodium channels after removal of inactivation. The Journal of general physiology. 77 [PubMed]

Rush AM, Dib-Hajj SD, Waxman SG. (2005). Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones. The Journal of physiology. 564 [PubMed]

Sakmann B, Neher E. (1995). Geometric parameters of pipettes and membrane patches Single Channel Recording.

Schmidt-Hieber C, Jonas P, Bischofberger J. (2007). Subthreshold dendritic signal processing and coincidence detection in dentate gyrus granule cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]

Schmidt-Hieber C, Jonas P, Bischofberger J. (2008). Action potential initiation and propagation in hippocampal mossy fibre axons. The Journal of physiology. 586 [PubMed]

Shu Y, Hasenstaub A, Duque A, Yu Y, McCormick DA. (2006). Modulation of intracortical synaptic potentials by presynaptic somatic membrane potential. Nature. 441 [PubMed]

Smith MR, Smith RD, Plummer NW, Meisler MH, Goldin AL. (1998). Functional analysis of the mouse Scn8a sodium channel. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18 [PubMed]

Stuart G, Spruston N, Sakmann B, Häusser M. (1997). Action potential initiation and backpropagation in neurons of the mammalian CNS. Trends in neurosciences. 20 [PubMed]

Vandenberg CA, Bezanilla F. (1991). A sodium channel gating model based on single channel, macroscopic ionic, and gating currents in the squid giant axon. Biophysical journal. 60 [PubMed]

Yu FH et al. (2003). Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]

References and models that cite this paper

Brette R. (2013). Sharpness of spike initiation in neurons explained by compartmentalization. PLoS computational biology. 9 [PubMed]

Chavlis S, Petrantonakis PC, Poirazi P. (2017). Dendrites of dentate gyrus granule cells contribute to pattern separation by controlling sparsity. Hippocampus. 27 [PubMed]

Hallermann S, de Kock CP, Stuart GJ, Kole MH. (2012). State and location dependence of action potential metabolic cost in cortical pyramidal neurons. Nature neuroscience. 15 [PubMed]

Jaffe DB, Brenner R. (2018). A computational model for how the fast afterhyperpolarization paradoxically increases gain in regularly firing neurons. Journal of neurophysiology. 119 [PubMed]

Ju H, Hines ML, Yu Y. (2016). Cable energy function of cortical axons. Scientific reports. 6 [PubMed]

Oláh VJ, Tarcsay G, Brunner J. (2021). Small size of recorded neuronal structures confines the accuracy in direct axonal voltage measurements. eNeuro. 8 [PubMed]

Pezo D, Soudry D, Orio P. (2014). Diffusion approximation-based simulation of stochastic ion channels: which method to use? Frontiers in computational neuroscience. 8 [PubMed]

Schmidt-Hieber C et al. (2017). Active dendritic integration as a mechanism for robust and precise grid cell firing. Nature neuroscience. 20 [PubMed]

Schneider CJ, Cuntz H, Soltesz I. (2014). Linking macroscopic with microscopic neuroanatomy using synthetic neuronal populations. PLoS computational biology. 10 [PubMed]

Schwarzacher SW, Cuntz H, Jedlicka P, Beining M, Mongiat LA. (2017). T2N as a new tool for robust electrophysiological modeling demonstrated for mature and adult-born dentate granule cells eLife.

Singh C, Levy WB. (2017). A consensus layer V pyramidal neuron can sustain interpulse-interval coding. PloS one. 12 [PubMed]

This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.