Brown SA, Moraru II, Schaff JC, Loew LM. (2011). Virtual NEURON: a strategy for merged biochemical and electrophysiological modeling. Journal of computational neuroscience. 31 [PubMed]

See more from authors: Brown SA · Moraru II · Schaff JC · Loew LM

References and models cited by this paper

Berridge MJ, Lipp P, Bootman MD. (2000). The versatility and universality of calcium signalling. Nature reviews. Molecular cell biology. 1 [PubMed]

Bhalla US, Bilitch DH, Bower JM. (1992). Rallpacks: a set of benchmarks for neuronal simulators. Trends in neurosciences. 15 [PubMed]

Booth V, Rinzel J, Kiehn O. (1997). Compartmental model of vertebrate motoneurons for Ca2+-dependent spiking and plateau potentials under pharmacological treatment. Journal of neurophysiology. 78 [PubMed]

Bower JM, Beeman D. (2003). The book of GENESIS exploring realistic neural models with the GEneral NEural SImulation System (2nd ed).

Bower JM, Beeman D. (2007). Constructing realistic neural simulations with GENESIS. Methods in molecular biology (Clifton, N.J.). 401 [PubMed]

Brown SA, Morgan F, Watras J, Loew LM. (2008). Analysis of phosphatidylinositol-4,5-bisphosphate signaling in cerebellar Purkinje spines. Biophysical journal. 95 [PubMed]

Burke RE, Fyffe RE, Moschovakis AK. (1994). Electrotonic architecture of cat gamma motoneurons. Journal of neurophysiology. 72 [PubMed]

Bush PC, Sejnowski TJ. (1993). Reduced compartmental models of neocortical pyramidal cells. Journal of neuroscience methods. 46 [PubMed]

Clements JD, Redman SJ. (1989). Cable properties of cat spinal motoneurones measured by combining voltage clamp, current clamp and intracellular staining. The Journal of physiology. 409 [PubMed]

De Schutter E, Bower JM. (1994). An active membrane model of the cerebellar Purkinje cell. I. Simulation of current clamps in slice. Journal of neurophysiology. 71 [PubMed]

Destexhe A, Babloyantz A, Sejnowski TJ. (1993). Ionic mechanisms for intrinsic slow oscillations in thalamic relay neurons. Biophysical journal. 65 [PubMed]

Di Gregorio E et al. (2010). Two Italian families with ITPR1 gene deletion presenting a broader phenotype of SCA15. Cerebellum (London, England). 9 [PubMed]

Douglas R, Martin KAC. (1992). Exploring cortical microcircuits: a combined anatomical, physiological, and computational approach Single Neuron Computation.

Finch EA, Augustine GJ. (1998). Local calcium signalling by inositol-1,4,5-trisphosphate in Purkinje cell dendrites. Nature. 396 [PubMed]

Fleshman JW, Segev I, Burke RB. (1988). Electrotonic architecture of type-identified alpha-motoneurons in the cat spinal cord. Journal of neurophysiology. 60 [PubMed]

Gilbert PF, Thach WT. (1977). Purkinje cell activity during motor learning. Brain research. 128 [PubMed]

HODGKIN AL, HUXLEY AF. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. The Journal of physiology. 117 [PubMed]

Hara K et al. (2008). Total deletion and a missense mutation of ITPR1 in Japanese SCA15 families. Neurology. 71 [PubMed]

Harris KM, Stevens JK. (1988). Dendritic spines of rat cerebellar Purkinje cells: serial electron microscopy with reference to their biophysical characteristics. The Journal of neuroscience : the official journal of the Society for Neuroscience. 8 [PubMed]

Hendrickson EB, Edgerton JR, Jaeger D. (2011). The capabilities and limitations of conductance-based compartmental neuron models with reduced branched or unbranched morphologies and active dendrites. Journal of computational neuroscience. 30 [PubMed]

Hernjak N et al. (2005). Modeling and analysis of calcium signaling events leading to long-term depression in cerebellar Purkinje cells. Biophysical journal. 89 [PubMed]

Hines ML, Carnevale NT. (1997). The NEURON simulation environment. Neural computation. 9 [PubMed]

Hines ML, Carnevale NT. (2001). NEURON: a tool for neuroscientists. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 7 [PubMed]

Ito M, Kano M. (1982). Long-lasting depression of parallel fiber-Purkinje cell transmission induced by conjunctive stimulation of parallel fibers and climbing fibers in the cerebellar cortex. Neuroscience letters. 33 [PubMed]

Iwaki A et al. (2008). Heterozygous deletion of ITPR1, but not SUMF1, in spinocerebellar ataxia type 16. Journal of medical genetics. 45 [PubMed]

Konnerth A, Dreessen J, Augustine GJ. (1992). Brief dendritic calcium signals initiate long-lasting synaptic depression in cerebellar Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. 89 [PubMed]

Loew LM, Schaff JC. (2001). The Virtual Cell: a software environment for computational cell biology. Trends in biotechnology. 19 [PubMed]

Major G, Larkman AU, Jonas P, Sakmann B, Jack JJ. (1994). Detailed passive cable models of whole-cell recorded CA3 pyramidal neurons in rat hippocampal slices. The Journal of neuroscience : the official journal of the Society for Neuroscience. 14 [PubMed]

Major G, Larkman AU, Stratford KJ, Mason AJR, Jack JJB. (1989). The modelling of pyramidal neurones in the visual cortex The Computing Neuron.

Manor Y, Gonczarowski J, Segev I. (1991). Propagation of action potentials along complex axonal trees. Model and implementation. Biophysical journal. 60 [PubMed]

Matsumoto M et al. (1996). Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor. Nature. 379 [PubMed]

McCormick DA, Huguenard JR. (1992). A model of the electrophysiological properties of thalamocortical relay neurons. Journal of neurophysiology. 68 [PubMed]

Missiaen L et al. (1997). Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin. Biochem J. 322 ( Pt 2)

Miyasho T et al. (2001). Low-threshold potassium channels and a low-threshold calcium channel regulate Ca2+ spike firing in the dendrites of cerebellar Purkinje neurons: a modeling study. Brain research. 891 [PubMed]

Moraru II, Schaff JC, Slepchenko BM, Loew LM. (2002). The virtual cell: an integrated modeling environment for experimental and computational cell biology. Annals of the New York Academy of Sciences. 971 [PubMed]

Napper RM, Harvey RJ. (1988). Quantitative study of the Purkinje cell dendritic spines in the rat cerebellum. The Journal of comparative neurology. 274 [PubMed]

Napper RM, Harvey RJ. (1988). Number of parallel fiber synapses on an individual Purkinje cell in the cerebellum of the rat. The Journal of comparative neurology. 274 [PubMed]

Ogura H, Matsumoto M, Mikoshiba K. (2001). Motor discoordination in mutant mice heterozygous for the type 1 inositol 1,4,5-trisphosphate receptor. Behavioural brain research. 122 [PubMed]

Pinsky PF, Rinzel J. (1994). Intrinsic and network rhythmogenesis in a reduced Traub model for CA3 neurons. Journal of computational neuroscience. 1 [PubMed]

RALL W. (1962). Electrophysiology of a dendritic neuron model. Biophysical journal. 2 [PubMed]

Rall W. (1969). Time constants and electrotonic length of membrane cylinders and neurons. Biophysical journal. 9 [PubMed]

Rall W, Agmon-snir H. (1998). Cable theory for dendritic neurons Methods In Neuronal Modeling: From Ions To Networks. 2

Rall W, Rinzel J. (1973). Branch input resistance and steady attenuation for input to one branch of a dendritic neuron model. Biophysical journal. 13 [PubMed]

Rapp M, Segev I, Yarom Y. (1994). Physiology, morphology and detailed passive models of guinea-pig cerebellar Purkinje cells. The Journal of physiology. 474 [PubMed]

Regehr WG, Mintz IM. (1994). Participation of multiple calcium channel types in transmission at single climbing fiber to Purkinje cell synapses. Neuron. 12 [PubMed]

Rinzel J, Rall W. (1974). Transient response in a dendritic neuron model for current injected at one branch. Biophysical journal. 14 [PubMed]

Sarkisov DV, Wang SS. (2008). Order-dependent coincidence detection in cerebellar Purkinje neurons at the inositol trisphosphate receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28 [PubMed]

Schaff J, Fink CC, Slepchenko B, Carson JH, Loew LM. (1997). A general computational framework for modeling cellular structure and function. Biophysical journal. 73 [PubMed]

Segev I, Yarom Y, Rapp M. (1992). The impact of parallel fiber background activity on the cable properties of cerebellar Purkinje cells Neural Comput. 4

Shelton DP. (1985). Membrane resistivity estimated for the Purkinje neuron by means of a passive computer model. Neuroscience. 14 [PubMed]

Street VA et al. (1997). The type 1 inositol 1,4,5-trisphosphate receptor gene is altered in the opisthotonos mouse. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17 [PubMed]

Takechi H, Eilers J, Konnerth A. (1998). A new class of synaptic response involving calcium release in dendritic spines. Nature. 396 [PubMed]

Traub RD, Wong RK, Miles R, Michelson H. (1991). A model of a CA3 hippocampal pyramidal neuron incorporating voltage-clamp data on intrinsic conductances. Journal of neurophysiology. 66 [PubMed]

Wang SS, Denk W, Häusser M. (2000). Coincidence detection in single dendritic spines mediated by calcium release. Nature neuroscience. 3 [PubMed]

Watanabe M. (2008). Molecular mechanisms governing competitive synaptic wiring in cerebellar Purkinje cells. The Tohoku journal of experimental medicine. 214 [PubMed]

van de Leemput J et al. (2007). Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans. PLoS genetics. 3 [PubMed]

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McDougal RA, Bulanova AS, Lytton WW. (2016). Reproducibility in Computational Neuroscience Models and Simulations. IEEE transactions on bio-medical engineering. 63 [PubMed]

McDougal RA, Hines ML, Lytton WW. (2013). Reaction-diffusion in the NEURON simulator. Frontiers in neuroinformatics. 7 [PubMed]

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