This python code implements a method to estimate synaptic conductances from single membrane potential traces (the "VmT method"), as described in Pospischil et al. (2009). The method uses a maximum likelihood procedure and was successfully tested using models and dynamic-clamp experiments in vitro (see paper for details).
Model Type: Synapse
Model Concept(s): Methods
Simulation Environment: Python
Pospischil M, Piwkowska Z, Bal T, Destexhe A. (2009). Extracting synaptic conductances from single membrane potential traces. Neuroscience. 158 [PubMed]