This model was used to confirm and support experimental data suggesting that the neuronal/circuitry changes associated with temporal lobe epilepsy, including Ih-dependent inductive mechanisms, can disrupt hippocampal theta function.
Model Type: Dendrite
Region(s) or Organism(s): Hippocampus
Cell Type(s): Hippocampus CA1 pyramidal GLU cell
Currents: I h
Simulation Environment: NEURON
Implementer(s): Migliore, Michele [Michele.Migliore at Yale.edu]