" ... Although existing models of motoneurons have indicated the distributed role of certain conductances in regulating firing, it is unclear how the spatial distribution of certain currents is ultimately shaping motoneuron output. Thus, it would be helpful to build a bridge between histological and electrophysiological data. The present report is based on the construction of a 3D motoneuron model based on available parameters applicable to the neonatal spinal cord. ..."
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Spinal cord lumbar motor neuron alpha ACh cell
Model Concept(s): Active Dendrites; Influence of Dendritic Geometry; Detailed Neuronal Models; Action Potentials
Simulation Environment: NEURON
References:
Ostroumov K. (2007). A new stochastic tridimensional model of neonatal rat spinal motoneuron for investigating compartmentalization of neuronal conductances and their influence on firing. Journal of neuroscience methods. 163 [PubMed]