Cardiac action potentials and pacemaker activity of sinoatrial node (DiFrancesco & Noble 1985)

"Equations have been developed to describe cardiac action potentials and pacemaker activity. The model takes account of extensive developments in experimental work ..."

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Cardiac atrial cell; Cardiac ventricular cell

Currents: I Na,t; I K; I h; I Calcium; I Potassium; Na/Ca exchanger; Na/K pump

Genes: HCN4

Model Concept(s): Action Potentials

Simulation Environment: NEURON

Implementer(s): Gannier, Francois [francois.gannier at]


DiFrancesco D, Noble D. (1985). A model of cardiac electrical activity incorporating ionic pumps and concentration changes. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 307 [PubMed]

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