Rescue of plasticity by a computationally predicted protocol (Liu et al. 2013)

" ... A computational model, which simulated molecular processes underlying long-term synaptic facilitation (LTF) induction, predicted a rescue protocol of five pulses of 5-HT at non-uniform interstimulus intervals that overcame the consequences of reduced CREB-binding protein (CBP) and restored LTF. ..."

Model Type: Synapse

Region(s) or Organism(s): Aplysia

Cell Type(s): Aplysia sensory neuron

Model Concept(s): Signaling pathways

Simulation Environment: XPPAUT

Implementer(s): Zhang, Yili [Yili.Zhang at]


Liu RY et al. (2013). Deficit in long-term synaptic plasticity is rescued by a computationally predicted stimulus protocol. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33 [PubMed]

This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.