Following a distal stimulation of a motor fibre, only a fraction of spinal motoneurons are able to produce a re-excitation of the initial segment leading to an orthodromically conducted action potential, known as recurrent discharge. In order to show the reciprocal interplay of the axonal initial segment and the soma leading to recurrent discharge in detail, a reduced model of a cat spinal motoneuron was developed.
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Spinal cord lumbar motor neuron alpha ACh cell
Model Concept(s): Recurrent Discharge
Simulation Environment: NEURON
Implementer(s): Balbi, Pietro [piero.balbi at fsm.it]
Balbi P, Martinoia S, Colombo R, Massobrio P. (2014). Modelling recurrent discharge in the spinal a-motoneuron: reappraisal of the F wave. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 125 [PubMed]