Izhikevich-based models of CA1 pyramidal cells, with parameters constrained based on a whole hippocampus preparation. Strongly and weakly adapting models based on the experimental data have been developed. Code produces example model output. The code will also be made available on OSB.
Model Type: Neuron or other electrically excitable cell
Region(s) or Organism(s): Hippocampus
Cell Type(s): Hippocampus CA1 pyramidal GLU cell; Abstract Izhikevich neuron
Model Concept(s): Simplified Models; Rebound firing
Simulation Environment: Brian; Python
References:
Ferguson KA, Huh CY, Amilhon B, Williams S, Skinner FK. (2014). Simple, biologically-constrained CA1 pyramidal cell models using an intact, whole hippocampus context. F1000Research. 3 [PubMed]