This two-variable simple model is derived based on patch-clamp recordings from the CA1 region of a whole hippocampus preparation of PV+ fast-firing cells. Since basket cells, axo-axonic cells and bistratified cells can be PV+ and fast-firing, this model could be representative of these cell types. The model code will also be made available on OSB.
Model Type: Neuron or other electrically excitable cell
Region(s) or Organism(s): Hippocampus
Cell Type(s): Hippocampus CA1 basket cell; Hippocampus CA1 bistratified cell; Hippocampus CA1 axo-axonic cell; Hippocampus CA1 PV+ fast-firing interneuron
Model Concept(s): Action Potentials
Simulation Environment: Brian; Python
References:
Ferguson KA, Huh CY, Amilhon B, Williams S, Skinner FK. (2013). Experimentally constrained CA1 fast-firing parvalbumin-positive interneuron network models exhibit sharp transitions into coherent high frequency rhythms. Frontiers in computational neuroscience. 7 [PubMed]