Ephaptic coupling in passive cable and MSO neuron models (Goldwyn & Rinzel 2016)

Simulation code to explore how the synchronous activity of a bundle of neurons generates extracellular voltage, and how this extracellular voltage influences the membrane potential of "nearby" neurons. A non-synaptic mechanism known as ephaptic coupling. A model of a passive cable population (including user-friendly matlab GUI) and a model of medial superior olive neurons are included.

Model Type: Neuron or other electrically excitable cell; Dendrite; Extracellular

Cell Type(s): Medial Superior Olive (MSO) cell

Currents: I Na,t; I K

Model Concept(s): Coincidence Detection; Extracellular Fields; Evoked LFP; Ephaptic coupling

Simulation Environment: MATLAB

Implementer(s): Goldwyn, Joshua [jhgoldwyn at gmail.com]


Goldwyn JH, Rinzel J. (2016). Neuronal coupling by endogenous electric fields: cable theory and applications to coincidence detector neurons in the auditory brain stem. Journal of neurophysiology. 115 [PubMed]

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