Code for simulating macroscopic currents of sodium channels (Nav1.1. to Nav1.9), by means of a single kinetic model. Intensity-voltage curves, normalized conductance-voltage relationship, steady-state availability and recovery from inactivation are simulated.
Model Type: Channel/Receptor
Currents: I Sodium
Model Concept(s): Markov-type model
Simulation Environment: NEURON
Implementer(s): Balbi, Pietro [piero.balbi at fsm.it]
Balbi P, Massobrio P, Hellgren Kotaleski J. (2017). A single Markov-type kinetic model accounting for the macroscopic currents of all human voltage-gated sodium channel isoforms. PLoS computational biology. 13 [PubMed]