Neuromuscular network model of gut motility (Barth et al 2017)

Here we develop an integrated neuromechanical model of the ENS and assess neurostimulation strategies for enhancing gut motility. The model includes a network of enteric neurons, smooth muscle fibers, and interstitial cells of Cajal, which regulate propulsion of a virtual pellet in a model of gut motility.

Model Type: Extracellular; Neuron or other electrically excitable cell

Region(s) or Organism(s): Enteric nervous system

Simulation Environment: Brian 2; Python

Implementer(s): Barth, Bradley [bradley.barth at]


Barth BB, Henriquez CS, Grill WM, Shen X. (2017). Electrical stimulation of gut motility guided by an in silico model. Journal of neural engineering. 14 [PubMed]

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