M-current in a collision detection neuron (LGMD model) (Dewell & Gabbiani 2018)

" ...In this study, we demonstrate that the LGMD (Lobula Giant Movement Detector) neuron exhibits a large M current, generated by noninactivating K channels, that shortens the temporal window of dendritic integration, regulates a firing mode switch between burst and isolated spiking, increases the precision of spike timing, and increases the reliability of spike propagation to downstream motor centers. ..."

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Locust Lobula Giant Movement Detector (LGMD) neuron

Currents: I M; I h; I K,Ca

Model Concept(s): Membrane Properties

Simulation Environment: NEURON

Implementer(s): Dewell, Richard Burkett [dewell at bcm.edu]; Gabbiani, F


Dewell RB, Gabbiani F. (2018). M current regulates firing mode and spike reliability in a collision-detecting neuron. Journal of neurophysiology. 120 [PubMed]

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