" ... Using both multicompartment Hodgkin-Huxley-type simulations and electrophysiological recordings in rodent brain slices, we find that increasing or decreasing the postsynaptic conductance of the set of thalamocortical inputs to one L4SS (Layer 4 Spiny Stellate) cell decreases the energy efficiency of information transmission from a single thalamocortical input. ..."
Model Type: Synapse
Cell Type(s): Neocortex spiny stellate cell
Model Concept(s): Information transfer
Simulation Environment: NEURON
Implementer(s): Renaud, Jolivet [renaud.jolivet at unige.ch]
References:
Harris JJ, Engl E, Attwell D, Jolivet RB. (2019). Energy-efficient information transfer at thalamocortical synapses. PLoS computational biology. 15 [PubMed]