Energy-efficient information transfer at thalamocortical synapses (Harris et al 2019)

" ... Using both multicompartment Hodgkin-Huxley-type simulations and electrophysiological recordings in rodent brain slices, we find that increasing or decreasing the postsynaptic conductance of the set of thalamocortical inputs to one L4SS (Layer 4 Spiny Stellate) cell decreases the energy efficiency of information transmission from a single thalamocortical input. ..."

Model Type: Synapse

Cell Type(s): Neocortex spiny stellate cell

Model Concept(s): Information transfer

Simulation Environment: NEURON

Implementer(s): Renaud, Jolivet [renaud.jolivet at]


Harris JJ, Engl E, Attwell D, Jolivet RB. (2019). Energy-efficient information transfer at thalamocortical synapses. PLoS computational biology. 15 [PubMed]

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