Spatial coupling tunes NMDA receptor responses via Ca2+ diffusion (Iacobucci and Popescu 2019)

This code implements a coupled markov model for analysis of positive or negative ion channel coupling from measured unitary currents in patch clamp recordings see our paper: Spatial Coupling Tunes NMDA Receptor Responses via Ca2+ Diffusion Gary J. Iacobucci and Gabriela K. Popescu Journal of Neuroscience 6 November 2019, 39 (45) 8831-8844; DOI:

Model Type: Synapse; Extracellular

Region(s) or Organism(s): Hippocampus

Currents: I Calcium

Receptors: NMDA

Transmitters: Glutamate

Model Concept(s): Synaptic Plasticity; Development

Simulation Environment: MATLAB


Iacobucci GJ, Popescu GK. (2019). Spatial Coupling Tunes NMDA Receptor Responses via Ca2+ Diffusion. The Journal of neuroscience : the official journal of the Society for Neuroscience. 39 [PubMed]

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