Voltage-gated conductances can counteract filtering effect of membrane capacitance (Heras et al '16)

Phenomenological inductance generated by voltage-gated ionic conductances (Na or K) can increase the gain bandwidth product of subthreshold signaling (e.g. psps) in a neuron, reducing the attenuation and slowing caused by membrane capacitance.

Model Type: Neuron or other electrically excitable cell

Region(s) or Organism(s): Honeybee (Apis mellifera); Blowfly (Calliphora vicina)

Cell Type(s): Insect photoreceptor

Currents: I K; I Sodium; I Potassium

Model Concept(s): Electrotonus; Membrane Properties; Invertebrate; Gain-bandwidth product (GBWP); Phenomenological inductance

Simulation Environment: Python; pHHotoreceptor

Implementer(s): Heras, Francisco J. H.


Heras FJ, Laughlin SB, Niven JE. (2016). Shunt peaking in neural membranes. Journal of the Royal Society, Interface. 13 [PubMed]

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