Look-Up Table Synapse (LUTsyn) models for AMPA and NMDA (Pham et al., 2021)


Fast input-output synapse model of glutamatergic receptors AMPA and NMDA that can capture nonlinear interactions via look-up table abstraction. Speeds are comparable to 'linear' exponential synapses. Download LUT files at: https://senselab.med.yale.edu/modeldb/data/267103/LUTs.zip

Model Type: Channel/Receptor; Synapse

Region(s) or Organism(s): Dentate gyrus

Receptors: AMPA; NMDA

Transmitters: Glutamate

Model Concept(s): Multiscale

Simulation Environment: NEURON

References:

Pham DJ, Yu GJ, Bouteiller JC, Berger TW. (2021). Bridging Hierarchies in Multi-Scale Models of Neural Systems: Look-Up Tables Enable Computationally Efficient Simulations of Non-linear Synaptic Dynamics Frontiers in computational neuroscience. 15 [PubMed]

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