Spatial constrains of GABAergic rheobase shift (Lombardi et al., 2021)

In this models we investigated how the threshold eGABA, at which GABAergic inhibition switches to excitation, depends on the spatiotemporal constrains in a ball-and-stick neurons and a neurons with a topology derived from an reconstructed neuron.

Model Type: Synapse; Neuron or other electrically excitable cell

Region(s) or Organism(s): Hippocampus

Cell Type(s): Hippocampus CA3 pyramidal GLU cell

Receptors: AMPA; GabaA

Transmitters: Glutamate; Gaba

Model Concept(s): Development; Action Potentials

Simulation Environment: NEURON

Implementer(s): Kilb, Werner [wkilb at]


Lombardi A, Luhmann HJ, Kilb W. (2021). Modelling the spatial and temporal constrains of the GABAergic influence on neuronal excitability PLoS computational biology. 17 [PubMed]

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