Signal integration in LGN cells (Briska et al 2003)


Computer models were used to investigate passive properties of lateral geniculate nucleus thalamocortical cells and thalamic interneurons based on in vitro whole-cell study. Two neurons of each type were characterized physiologically and morphologically. Differences in the attenuation of propagated signals depend on both cell morphology and signal frequency. See the paper for details.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Thalamus geniculate nucleus/lateral principal GLU cell

Model Concept(s): Influence of Dendritic Geometry; Vision

Simulation Environment: NEURON

Implementer(s): Lytton, William [bill.lytton at downstate.edu]

References:

Briska AM, Uhlrich DJ, Lytton WW. (2003). Computer model of passive signal integration based on whole-cell in vitro studies of rat lateral geniculate nucleus. The European journal of neuroscience. 17 [PubMed]


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