Minimal cell model (Av-Ron et al 1991)

The minimal cell model (MCM) is a reduced Hodgkin-Huxley model that can exhibit excitable and oscillatory behavior. It consists of two ordinary differential equations, dV/dt for membrane voltage and dW/dt for potassium activation and sodium inactivation. The MCM has a stable membrane potential of -60mV. With constant input current of 10uA/cm2, it exhibits oscillations of 150Hz. It is based on the work by FitzHugh and Rinzel.

Model Type: Neuron or other electrically excitable cell

Currents: I Sodium; I Potassium

Model Concept(s): Simplified Models; Action Potentials; Invertebrate

Simulation Environment: SNNAP

Implementer(s): Av-Ron, Evyatar [eav-ron at]


Av-Ron E, Parnas H, Segel LA. (1991). A minimal biophysical model for an excitable and oscillatory neuron. Biological cybernetics. 65 [PubMed]

This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.